Overview

This manual sets out the process for how new guidance topics and updates to existing NICE guidance are identified, prioritised and routed at NICE, and the decision-making framework used by the NICE prioritisation board.

Last reviewed: 31 March 2025

We removed the appendix on highly specialised technologies in this manual in favour of publishing a guide on routing criteria for highly specialised technologies. Links were updated throughout this manual to the new guide.

This process manual updates and replaces the manual on NICE health technology evaluation topic selection, and section 1.4 of the manual on developing NICE guidelines.