Before 2022, we used different processes for assessing technologies. You can view the process types, along with brief descriptions for each of them, on this page.
Single technology appraisal
This is a technology appraisal that assesses a single drug or treatment.
When it's used
We use the single technology appraisal process for new technologies - usually new pharmaceutical products or licence extensions for existing products. We also use it for reviews of some published appraisals.
This process enables us to produce guidance soon after the technology is introduced in the UK.
We updated our single technology appraisal process in April 2018. Single technology appraisals developed from April 2018 onwards will use the updated process. Appraisals that started development before April 2018 will use the pre-April 2018 process.
Single technology appraisal timeline
A step-by-step guide to our single technology appraisal process
Multiple technology appraisal
This is a technology appraisal that assesses several drugs or treatments used for one condition.
When it's used
We use the multiple technology appraisal process if a new topic for an appraisal is particularly complex and not suited for the single technology appraisal process. It's also used for reviews of published appraisals.
Multiple technology appraisal timeline
A step-by-step guide to the multiple technology appraisal process
Cost comparison appraisal
The cost comparison process aims to provide quicker access for patients to the most cost effective new treatments.
When it's used
A technology will be appraised through this process if a cost comparison case can be made that shows it's likely to provide similar or greater health benefits at similar or lower cost than technologies already recommended in technology appraisal guidance for the same indication.
If a positive recommendation is made through the cost comparison process, NHS England commissioners have committed to providing funding for the technologies within 30 days of guidance publication.
Previous process and methods guides
- Guide to the processes of technology appraisal 2014 to 2018
- Guide to the processes of technology appraisal 2014 to 2018 (PDF)
- Guide to the processes of technology appraisal – commercial and managed access interim addendum (PDF)
- Guide to the methods of technology appraisal
- Cost comparison methods (PDF)
- Cancer Drugs Fund process and methods (PDF)
- Guidance for industry when completing the Summary of information for patients (SIP) (Word)
- Summary of information for patients (SIP) template (Word)
- Pre-April 2018 guide to the processes of technology appraisal: multiple technology appraisals and single technology appraisals (PDF)
- Pre-2014 guide to the single technology appraisal process (PDF)
- Pre-2014 guide to the multiple technology appraisal process (PDF)