Recommendation ID
CG126/1
Question
Adding a newer anti-anginal drug to a calcium channel blocker:- What is the clinical and cost effectiveness of adding a newer anti-anginal drug (nicorandil, ivabradine or ranolazine) to a calcium channel blocker for treating stable angina?
Any explanatory notes
(if applicable)
Why this is important:- We do not know the long-term clinical and cost effectiveness of adding a
newer anti-anginal drug to a calcium channel blocker in people with stable angina. We propose a double-blind placebo-controlled randomised trial comparing the addition of a newer anti-anginal drug to a calcium channel blocker with a calcium channel blocker alone in people with stable angina
whose symptoms are not being controlled. Endpoints would include symptom severity, quality of life, long-term morbidity and mortality, and cost effectiveness. The results of the trial would influence clinical practice and inform future updates of key recommendations in this guideline.

Source guidance details

Comes from guidance
Stable angina: management
Number
CG126
Date issued
July 2011

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No