Recommendation ID
NG124/3
Question

What is the effectiveness of diuretics compared with placebo in preventing bronchopulmonary dysplasia (BPD) in preterm babies on respiratory support?

Any explanatory notes
(if applicable)

The evidence on the use of diuretics in preterm babies on respiratory support was very limited. None of the studies identified assessed critical outcomes such as mortality before discharge, BPD or neurodevelopmental outcomes. Although the studies looked at short-term adverse effects associated with diuretics, it was not clear whether there was an increased risk of adverse effects because of the small sample size of the studies.

Because of the limited evidence and lack of clinical consensus, the committee could not make any recommendations for or against diuretic use in preterm babies on respiratory support. Instead, the committee recommended that further research be done in this area.


Source guidance details

Comes from guidance
Specialist neonatal respiratory care for babies born preterm
Number
NG124
Date issued
April 2019

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 02/04/2019