Attention deficit hyperactivity disorder: diagnosis and management

Recommendation ID: NG87/2
Question: Medication choice in people with coexisting conditions:- What is the clinical and cost effectiveness of ADHD medications in people with ADHD and tic disorders, a history of psychosis or mania, or personality disorder?
Any explanatory notes (if applicable): Why is this important:- No evidence was identified to justify different medication choices in people with ADHD and tic disorders, a history of psychosis or mania, or emotional dysregulation. These groups are often excluded from trials. There are reasons (for example, mechanism of action of medication options, previous reports of adverse effects) to suspect that these groups may respond differently to different drugs, but a lack of trials to confirm this. Primarily there are some concerns that stimulant
medication may worsen the symptoms of any of these coexisting conditions and therefore nonstimulant medication should be preferred.

Source guidance details

Comes from guidance: Attention deficit hyperactivity disorder: diagnosis and management
Number: NG87
Date issued: March 2018

Is this a recommendation for the use of a technology only in the context of research?	No
Is it a recommendation that suggests collection of data or the establishment of a register?	No
Last Reviewed	31/03/2018