Advice
Appendix: search strategy and evidence selection
Search strategy
For the clinical evidence
Embase 1980 to 2015 October 22, Ovid MEDLINE(R) In‑Process & Other Non‑Indexed Citations and Ovid MEDLINE(R) 1946 to Present; searched 22 October 2015
Search strategy 1: Device and Coronary Artery Disease
1. CT.mp.
2. computed tomography.mp.
3. Coronary Artery Disease.mp. or Coronary Artery Disease/
4. Coronary Artery Disease/ or Coronary Disease/ or Coronary Angiography/
5. CAD.mp. [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]
6. myocardial infarction.mp. or Myocardial Infarction/
7. myocardial ischemia.mp. or Myocardial Ischemia/
8. Aquilion.mp.
9. Prime.mp.
10. Toshiba.mp.
11. 1 or 2
12. 3 or 4 or 5 or 6 or 7
13. 8 or 9 or 10
14. 11 and 12 and 13
15. limit 14 to yr="2012 ‑ current"
16. limit 15 to english language
Search strategy 2: Population and CT
1. CT.tw.
2. computed tomography.tw.
3. Coronary Artery Disease.tw. or Coronary Artery Disease/
4. Coronary Artery Disease/ or Coronary Disease/ or Coronary Angiography/
5. (coronary adj2 disease).tw.
6. CAD.tw.
7. myocardial infarction.tw. or Myocardial Infarction/
8. myocardial ischemia.tw. or Myocardial Ischemia/
9. high heart rate.tw.
10. arrhythmia.tw.
11. (tachycardia or tachyarrhythmia).tw.
12. (obesity or obese).tw.
13. stents.tw.
14. bypass grafts.tw.
15. calcium score.tw.
16. 1 or 2
17. 3 or 4 or 5 or 6
18. 7 or 8 or 9 or 11 or 12 or 13 or 14 or 15
19. 16 and 17 and 18
20. 19 not (perfusion or gene or neuro* or immuno* or simulat* or child* or youth or baby or infant).tw.
21. limit 20 to english language
22. limit 21 to yr="2012‑current"
For the economic evidence
Embase 1974 to 2015 October 28, Ovid MEDLINE(R) In‑Process & Other Non‑Indexed Citations and Ovid MEDLINE(R) 1946 to Present; Searched on 29October 2015
1. CT.mp.
2. computed tomography.mp.
3. Coronary Artery Disease.mp. or Coronary Artery Disease/
4. Coronary Artery Disease/ or Coronary Disease/ or Coronary Angiography/
5. CAD.mp.
6. myocardial infarction.mp. or Myocardial Infarction/
7. myocardial ischemia.mp. or Myocardial Ischemia/
8. Aquilion.mp.
9. Prime.mp.
10. Toshiba.mp.
11. 1 or 2
12. 3 or 4 or 5 or 6 or 7
13. 8 or 9 or 10
14. 11 and 12 and 13
15. cost*.mp.
16. economic*.mp.
17. 15 or 16
18. 14 and 17
19. limit 18 to english language
20. limit 19 to yr="2012 ‑Current"
Cochrane Database of Systematic Reviews: Issue 10 of 12, October 2015
Cochrane Central Register of Controlled Trials: Issue 9 of 12, September 2015
Database of Abstracts of Reviews of Effect: Issue 2 of 4, April 2015
Cochrane Methodology Register: Issue 3 of 4, July 2012
Health Technology Assessment Database: Issue 3 of 4, July 2015
NHS Economic Evaluation Database: Issue 2 of 4, April 2015
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CT
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computed tomography
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Coronary Artery Disease
-
Coronary Disease or Coronary Angiography
-
CAD
-
myocardial infarction
-
myocardial ischemia
-
Aquilion
-
Prime
-
Toshiba
-
#1 or #2
-
#3 or #4 or #5 or #6 or #7
-
#8 or #9 or #10
-
#11 and #12 and #13
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cost*
-
economic*
-
#15 or #16
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#14 and #17 Publication Year from 2012 to 2015
Evidence selection
Evidence was selected based on the following criteria:
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Population: patients with suspected or known CAD with 1 of the following conditions:
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obesity
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high levels of coronary calcium (greater than 400 Agatston units [AU])
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high heart rates (more than 65 beats per minute) that cannot be lowered with drugs
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arrhythmias (irregular heart rhythm)
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stents
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previous bypass grafts.
-
-
Intervention: Toshiba Aquilion PRIME.
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Comparator: ICA, cardiac MRI, SPECT, ECHO.
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Outcomes: diagnostic test accuracy, indeterminacy, radiation exposure and clinical outcomes including side effects associated with the use of contrast medium, major adverse cardiac events, or mortality.
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Exclusion criteria: case studies, editorials, letters, reviews, conference proceedings/abstracts, animal studies, non‑English language studies, studies not using the Aquilion PRIME.
For the clinical evidence
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Total number of publications reviewed: 1972
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Total number of publications considered relevant: 0
-
Total number of publications selected for inclusion in this briefing: 0
For the economic evidence
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Total abstracts: 21
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Duplicates: 1
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Abstracts reviewed: 20
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Full papers reviewed: 0
-
Studies for review: 0