Guidance
3 Committee considerations
The evidence
3.1 To inform the committee, NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 5 sources, which was discussed by the committee. The evidence included 1 randomised controlled trial (in 2 publications), 2 case series and 1 case report, and is presented in table 2 of the interventional procedures overview.
3.2 The specialist advisers and the committee considered the key efficacy outcomes to be: repair of prolapse and reduction of symptoms.
3.3 The specialist advisers and the committee considered the key safety outcomes to be: pain, infection and mesh erosion into the vagina, bladder, urethra or bowel.
3.4 Patient commentary was sought but none was received.