3.1
NICE did a rapid review of the published literature on the efficacy and safety of this procedure. This comprised a comprehensive literature search and detailed review of the evidence from 8 sources, which was discussed by the committee. The evidence included 1 systematic review and network meta-analysis, 3 randomised controlled trials, 2 non-randomised comparative studies and 1 case series. The committee also considered safety data from 3 implant summary reports for the Profemur L Modular Stem, Profemur L Classic Stem and Procotyl L Cup, provided by the National Joint Registry. It is presented in the summary of key evidence section in the interventional procedures overview. Other relevant literature is in the appendix of the overview.