3.1
The key clinical outcomes for ENDURALIFE‑powered cardiac resynchronisation therapy-defibrillator (CRT‑D) devices in the decision problem were:
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device survival
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battery survival (or time to battery depletion)
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CRT‑D component failure
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number of invasive procedures including CRT‑D replacements
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incidence of complications after replacement procedures for battery depletion or CRT‑D component failure (as per definitions in the REPLACE registry)
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inpatient admissions and bed days (related to interventions)
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death
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patient satisfaction
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quality of life
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device-related adverse events.