Rezum for treating lower urinary tract symptoms secondary to benign prostatic hyperplasia

1.1 Evidence supports the case for adopting Rezum for treating lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) in the NHS. Rezum relieves LUTS and improves quality of life.

1.2 Rezum is a minimally invasive procedure. It should be considered as a treatment option for people with:

1.3 Cost modelling estimates that Rezum is cost saving compared with standard treatments such as transurethral resection of the prostate (TURP) and holmium laser enucleation of the prostate (HoLEP) by more than £550 per person over 4 years. Savings compared with UroLift are uncertain. This is because of uncertainty about some of the assumptions in the cost modelling for that comparison.

Why the committee made these recommendations

Rezum is a minimally invasive procedure that involves injecting steam to destroy excess prostate tissue. Clinical evidence shows that using the Rezum procedure relieves LUTS caused by BPH in men with moderate to severe symptoms who have a moderately enlarged prostate. Evidence also shows that using Rezum is associated with improved quality of life and a low risk of sexual dysfunction. Cost analyses suggest that when Rezum is used as an alternative to standard treatment, such as TURP or HoLEP, it is likely to lead to cost savings because it is done as day surgery with reduced operating and recovery costs.