2 Information about quizartinib

Marketing authorisation indication

2.1

Quizartinib (Vanflyta, Daiichi Sankyo) is indicated 'in combination with standard cytarabine and anthracycline induction and standard cytarabine consolidation chemotherapy, followed by Vanflyta single-agent maintenance therapy for adult patients with newly diagnosed acute myeloid leukaemia (AML) that is FLT3‑ITD positive'.

Dosage in the marketing authorisation

Price

2.3

The list prices of quizartinib are £6,451 for a 28‑pack of 17.7 mg tablets, and £12,902 for a 56‑pack of 26.5 mg tablets (excluding VAT; BNF online accessed August 2024).

2.4

The company has a commercial arrangement. This makes quizartinib available to the NHS with a discount. The size of the discount is commercial in confidence.