Methadone and buprenorphine for the management of opioid dependence

  • Technology appraisal guidance
  • TA114
  • Published: 
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6 Recommendations for further research

6.1 Randomised controlled trials conducted in the UK comparing methadone and buprenorphine using flexible dosing are required.

6.2 Randomised controlled trials conducted in the UK comparing high-dose methadone and high-dose buprenorphine are required.

6.3 Research examining the impact of supervised consumption on the prevention of overdose is needed.