7 Sources of evidence considered by the Committee

The Evidence Review Group (ERG) report for this appraisal was prepared by Liverpool Reviews and Implementation Group (LRiG)

  • Brown T, Boland A, Bagust A, et al. Gefitinib for the first-line treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC), November 2009

The following organisations accepted the invitation to participate in this appraisal as consultees and commentators. They were invited to comment on the draft scope, the ERG report and the appraisal consultation document (ACD). Manufacturers, or sponsors, were also invited to make written submissions. Professional or specialist and patient or carer groups and other consultees had the opportunity to give their expert views. Manufacturers, or sponsors, professional or specialist and patient or carer groups, and other consultees, also have the opportunity to appeal against the final appraisal determination.

Manufacturer or sponsor:

  • AstraZeneca

Professional or specialist and patient or carer groups:

  • British Thoracic Society (Lung Cancer and Mesothelioma Working Party)

  • Cancer Research UK

  • Macmillan Cancer Support

  • National Lung Cancer Forum for Nurses

  • Royal College of Nursing

  • Royal College of Pathologists

  • Royal College of Physicians, Medical Oncology Joint Special Committee

  • Roy Castle Lung Cancer Foundation

  • UK Oncology Nursing Society

Other consultees:

  • Department of Health

  • Kirklees Primary Care Trust

  • Welsh Assembly Government

Commentator organisations (did not provide written evidence and without the right of appeal):

  • British Thoracic Oncology Group

  • Commissioning Support Appraisals Service

  • Department of Health, Social Services and Public Safety for Northern Ireland

  • Eli Lilly

  • Medac

  • NHS Quality Improvement Scotland

  • Pierre Fabre

  • Sanofi Aventis

The following individuals were selected from clinical specialist and patient advocate nominations from the non-manufacturer or sponsor consultees and commentators. They gave their expert personal view on gefitinib by attending the initial Committee discussion and providing written evidence to the Committee. They were also invited to comment on the ACD.

  • Professor Mike Lind, Consultant Medical Oncologist, Castle Hill Hospital, nominated by the Royal College of Physicians – clinical specialist

Representatives from the following manufacturer or sponsor attended Committee Meetings. They contributed only when asked by the Committee chair to clarify specific issues and comment on factual accuracy.

  • AstraZeneca