Mepolizumab for treating severe eosinophilic asthma

2.1 Mepolizumab (Nucala, GlaxoSmithKline) has a marketing authorisation in the UK as an 'add-on treatment for severe refractory eosinophilic asthma in adults, adolescents and children aged 6 years and older'.

2.2 Mepolizumab is available as a powder for solution for injection in vials, or as a solution for injection in pre-filled syringes and pre-filled pens. The dosage schedule is available in the summary of product characteristics.

2.3 The list price of mepolizumab is £840 per 100 mg dose (excluding VAT; BNF online, accessed November 2020). The company has a commercial arrangement. This makes mepolizumab available to the NHS with a discount. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.