Guidance

5 Recommendations for further research

5 Recommendations for further research

5.1 The committee recommends more research on:

  • the accuracy of PredictSURE IBD and IBDX tests in identifying people at high or low risk of following a severe course of Crohn's disease

  • how PredictSURE IBD and IBDX tests, when used alongside clinical features, affect clinical decisions about whether step-up or top-down treatment is offered

  • the clinical outcomes and costs resulting from a top-down treatment strategy compared with a step-up treatment strategy

  • how PredictSURE IBD and IBDX tests affect clinical outcomes once someone has been assigned to top-down or step-up treatment, considering the different pathways that children and adults may follow.