Further research is recommended on:
- The accuracy of EarlyCDT Lung, and the validity of the risk models used to combine EarlyCDT Lung results with the Brock and the Herder risk models.
- The impact of EarlyCDT Lung on clinical management decisions.
A large retrospective audit is recommended to:
- Understand how patient and nodule characteristics impact on malignancy prevalence and disease progression.
- Understand current practice regarding clinical management of people with intermediate-risk lung nodules.
- Determine the clinical consequences of CT surveillance, including the likelihood of disease progression during CT surveillance.
- Determine the likelihood and impact of unnecessary biopsy or resection of indolent and benign nodules
- If existing data on these points is limited or not routinely collected, a prospective data collection should be undertaken to obtain it.