Contrast-enhanced ultrasound with SonoVue is recommended for characterising incidentally detected focal liver lesions in adults in whom an unenhanced ultrasound scan is inconclusive. An unenhanced ultrasound scan in which a focal liver lesion is detected, but not characterised, is defined as inconclusive.
Contrast-enhanced ultrasound with SonoVue is recommended for investigating potential liver metastases in adults:
if contrast-enhanced computed tomography (CT) is not clinically appropriate, is not accessible or is not acceptable to the person, and
in whom an unenhanced ultrasound scan is unsatisfactory and contrast is needed for further diagnosis.
Contrast-enhanced ultrasound with SonoVue is recommended for characterising focal liver lesions in adults whose cirrhosis is being monitored:
if contrast-enhanced magnetic resonance imaging (MRI) is not clinically appropriate, is not accessible or is not acceptable to the person, and
when unenhanced ultrasound scan is inconclusive.