Suggested remit: To appraise the clinical and cost effectiveness of talquetamab within its marketing authorisation for treating relapsed or refractory multiple myeloma after 3 treatments.
 
Status In progress
Technology type Medicine
Decision Selected
Reason for decision Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process STA Standard
ID number 5082

Provisional Schedule

Committee meeting 12 August 2025
Expected publication 15 October 2025

Project Team

Project lead Louise Jafferally

Email enquiries

External Assessment Group Warwick Evidence, Warwick Medical School, University of Warwick

Stakeholders

Companies sponsors Johnson & Johnson (talquetamab)
Others Department of Health and Social Care
  NHS England
Patient carer groups Blood Cancer UK
  Myeloma UK
Professional groups Association of Cancer Physicians
  Cancer Research UK
  Royal College of Pathologists
  Royal College of Physicians
  Royal College of Radiologists
  UK Myeloma Society
Associated public health groups None
Comparator companies GlaxoSmithKline (belantamab) (confidentiality agreement signed, participating)
  Menarini Stemline (selinexor) (confidentiality agreement signed, participating)
  Pfizer (bortezomib) (confidentiality agreement signed, participating)
  Sanofi (isatuximab) (confidentiality agreement signed, participating)
  Aspire Pharma (bortezomib) (confidentiality agreement not signed, not participating)
  Aurobindo Pharma (bortezomib) (confidentiality agreement not signed, not participating)
  Biotech Pharma (bortezomib) (confidentiality agreement not signed, not participating)
  Bristol Myers Squibb (pomalidomide) (confidentiality agreement not signed, not participating)
  Dr Reddy’s Laboratories (bortezomib) (confidentiality agreement not signed, not participating)
  Johnson & Johnson (bortezomib, teclistamab) (confidentiality agreement not signed, not participating)
  MSN Laboratories Europe (bortezomib) (confidentiality agreement not signed, not participating)
  Pharmaand GmbH (panobinostat) (confidentiality agreement not signed, not participating) (confidentiality agreement not signed, not participating)
  Sandoz (bortezomib) (confidentiality agreement not signed, not participating)
  Sun Pharma (bortezomib) (confidentiality agreement not signed, not participating)
  Thornton and Ross (bortezomib) (confidentiality agreement not signed, not participating)
  Tillomed Laboratories (bortezomib) (confidentiality agreement not signed, not participating)
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary
  Department of Health - Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  NHS Wales Joint Commissioning Committee
  Scottish Medicines Consortium
  Welsh Government
Relevant research groups Institute of Cancer Research

Timeline

Key events during the development of the guidance:

Date Update
13 January 2025 Invitation to participate
06 November 2024 - 04 December 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 5082
06 November 2024 In progress. Scoping commencing
23 February 2022 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual