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Technology appraisal guidance (325)
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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
Pitolisant for treating narcolepsy in children and young people 6 to 17 years ID6353
Technology appraisal guidance
TBC
Pneumonia: diagnosis and management (update)
NICE guideline
TBC
Port Delivery System with ranibizumab for treating wet age-related macular degeneration [ID3983]
Technology appraisal guidance
TBC
Pralsetinib for thyroid cancer [ID4018]
Technology appraisal guidance
TBC
Pulsed field ablation for atrial fibrillation
Interventional procedures guidance
9 July 2025
Regorafenib for treating advanced gastrointestinal stromal tumours [ID1056]
Technology appraisal guidance
15 November 2017
Rehabilitation for chronic neurological disorders including acquired brain injury
NICE guideline
16 July 2025
Relugolix–estradiol–norethisterone for treating symptoms of endometriosis [ID3982]
Technology appraisal guidance
TBC
Renal cell carcinoma Pathways Pilot [ID6186]
Technology appraisal guidance
TBC
Repotrectinib for treating ROS1-positive advanced non-small-cell lung cancer [ID6277]
Technology appraisal guidance
TBC
Retifanlimab with chemotherapy for untreated PD-L1-positive metastatic non-small-cell lung cancer TSID 12007
Technology appraisal guidance
TBC
Ribociclib in combination with endocrine therapy and goserelin for previously untreated hormone receptor-positive, HER2-negative advanced breast cancer in premenopausal women (ID1307)
Technology appraisal guidance
TBC
Ribociclib with an aromatase inhibitor for adjuvant treatment of hormone receptor-positive, HER2-negative early breast cancer [ID6153]
Technology appraisal guidance
18 June 2025
Rivogenlecleucel for treating haematological cancers in children and young people undergoing haploidentical haematopoietic stem cell transplant [ID1601]
Technology appraisal guidance
TBC
Rivogenlecleucel for treating haematological non-malignant diseases in children and young people undergoing haploidentical haematopoietic stem cell transplant [ID1496]
Technology appraisal guidance
TBC
Robot-assisted surgery for orthopaedic procedures: early value assessment
Health technology evaluation
31 March 2025
Robot-assisted surgery for soft-tissue procedures: early value assessment
Health technology evaluation
TBC
Ropeginterferon alfa-2b for treating polycythaemia vera without symptomatic splenomegaly [ID1596]
Technology appraisal guidance
TBC
Rozanolixizumab for treating antibody-positive generalised myasthenia gravis [ID5092]
Technology appraisal guidance
TBC
Rucaparib for maintenance treatment of advanced ovarian, fallopian tube and peritoneal cancer after response to first-line platinum-based chemotherapy [ID5100]
Technology appraisal guidance
TBC
Ruxolitinib for treating acute graft versus host disease refractory to corticosteroids in people aged 12 and over [ID6377]
Technology appraisal guidance
29 January 2025
Ruxolitinib for treating moderate to severe chronic graft-versus-host disease after an allogeneic stem cell transplant in people 28 days to 17 years [ID6427]
Technology appraisal guidance
TBC
Ruxolitinib for treating non-segmental vitiligo in people 12 years and over [ID3998]
Technology appraisal guidance
TBC
Sacituzumab govitecan for treating advanced non-small-cell lung cancer after platinum-based chemotherapy and a PD-1 or PD-L1 inhibitor [ID6375]
Technology appraisal guidance
TBC
Sacituzumab govitecan for treating hormone receptor-positive HER2-negative metastatic breast cancer after 2 or more therapies [ID4033]
Technology appraisal guidance
TBC
Sacituzumab govitecan for treating unresectable metastatic urothelial cancer [ID6150]
Technology appraisal guidance
TBC
Sacral nerve stimulation for idiopathic chronic non-obstructive urinary retention
Interventional procedures guidance
TBC
Sebetralstat for treating acute attacks of hereditary angioedema in people aged 12 and over ID6284
Technology appraisal guidance
TBC
Secukinumab for treating enthesitis-related arthritis or juvenile psoriatic arthritis [ID3738]
Technology appraisal guidance
TBC
Seladelpar for previously treated primary biliary cholangitis ID6429
Technology appraisal guidance
TBC
Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a cancer drug in people 12 years and over (managed access review of TA742) [ID6288]
Technology appraisal guidance
30 October 2024
Selpercatinib for advanced thyroid cancer with RET alterations that has not been treated with systemic therapy [ID6132]
Technology appraisal guidance
TBC
Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer (MA review of TA760) [ID6293]
Technology appraisal guidance
TBC
Selpercatinib for treating RET fusion-positive advanced solid tumours in people aged 12 and over with no other treatment options [ID6273]
Technology appraisal guidance
TBC
Selpercatinib for untreated RET-positive advanced thyroid cancer [ID6183]
Technology appraisal guidance
TBC
Semaglutide for preventing major cardiovascular events in people with cardiovascular disease and living with overweight or obesity ID6441
Technology appraisal guidance
TBC
Serplulimab with carboplatin and etoposide for untreated extensive-stage small-cell lung cancer ID6346
Technology appraisal guidance
TBC
Sipavibart for preventing COVID 19 [ID6282]
Technology appraisal guidance
TBC
Sirolimus gel for treating facial angiofibroma from tuberous sclerosis complex in people 6 years and older (review of TA972) [ID6440]
Technology appraisal guidance
12 November 2025
Slide sheets for repositioning or moving a person on or from a bed: Late Stage Assessment
Health technology evaluation
28 May 2025
Sodium phenylbutyrate–ursodoxicoltaurine for treating amyotrophic lateral sclerosis [ID6246]
Technology appraisal guidance
TBC
Sodium zirconium cyclosilicate for treating hyperkalaemia (partial review of TA599) [ID6439]
Technology appraisal guidance
13 August 2025
Somapacitan for treating growth hormone deficiency in children [ID6178]
Technology appraisal guidance
TBC
Sotatercept for treating pulmonary arterial hypertension [ID6163]
Technology appraisal guidance
15 October 2025
Soticlestat for treating seizures associated with Lennox–Gastaut syndrome in people 2 years and over TSID 10632
Technology appraisal guidance
TBC
Sotorasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (MA review of TA781) [ID6287]
Technology appraisal guidance
26 February 2025
SpaceOAR hydrogel spacer for reducing rectal toxicity during radiotherapy for prostate cancer (Suspended – referred to technology appraisals)
Medical technologies guidance
TBC
Sparsentan for treating primary IgA nephropathy [ID6308]
Technology appraisal guidance
30 April 2025
Spartalizumab with dabrafenib and trametinib for untreated BRAF V600 mutation-positive unresectable or metastatic melanoma [ID1668]
Technology appraisal guidance
21 April 2021
Spesolimab for preventing generalised pustular psoriasis flares [ID6216]
Technology appraisal guidance
TBC
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