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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
Canagliflozin for treating chronic kidney disease in people with type 2 diabetes [ID1653]
Technology appraisal guidance
TBC
Capivasertib with fulvestrant for treating hormone receptor-positive HER2-negative advanced breast cancer after endocrine treatment [ID6370]
Technology appraisal guidance
5 March 2025
Capivasertib with paclitaxel for untreated metastatic triple-negative breast cancer [ID6383]
Technology appraisal guidance
TBC
Cediranib with olaparib for treating recurrent platinum-resistant ovarian, fallopian tube or primary peritoneal cancer after 3 therapies [ID1639]
Technology appraisal guidance
TBC
Cemiplimab with platinum-based chemotherapy for untreated advanced non-small-cell lung cancer [ID3949]
Technology appraisal guidance
30 April 2025
Ciltacabtagene autoleucel for treating relapsed and lenalidomide-refractory multiple myeloma after 1 to 3 therapies [ID4012]
Technology appraisal guidance
TBC
Cimavax for treating wild-type EGFR-positive non-small-cell lung cancer [1259]
Technology appraisal guidance
TBC
Cladribine for treating relapsing multiple sclerosis [ID6263]
Technology appraisal guidance
5 February 2025
Cobolimab with dostarlimab and docetaxel for treating advanced non-small-cell lung cancer after anti-PD-L1 treatment and chemotherapy [ID6398]
Technology appraisal guidance
TBC
Colon cancer (adjuvant) - irinotecan [ID379]
Technology appraisal guidance
TBC
Cositecan for treating platinum or taxane resistant advanced, mucinous, epithelial ovarian cancer [ID826]
Technology appraisal guidance
TBC
Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer (MA review of TA529) [ID6289]
Technology appraisal guidance
4 December 2024
Dapagliflozin for treating chronic kidney disease [ID6411]
Technology appraisal guidance
TBC
Daprodustat for treating anaemia in people with chronic kidney disease [ID3987]
Technology appraisal guidance
TBC
Daratumumab with bortezomib, lenalidomide and dexamethasone for untreated multiple myeloma when high-dose chemotherapy with stem cell transplant is unsuitable [ID3843]
Technology appraisal guidance
TBC
Darolutamide with androgen deprivation therapy for treating hormone-sensitive metastatic prostate cancer ID6452
Technology appraisal guidance
TBC
Dasatinib for treating Philadelphia-chromosome-positive acute lymphoblastic leukaemia in children and adults ID1297
Technology appraisal guidance
TBC
Dasatinib for treating Philadelphia-chromosome-positive acute lymphoblastic leukaemia in children and adults ID1297
Technology appraisal guidance
28 July 2021
Datopotamab deruxtecan for previously treated hormone receptor-positive HER2-negative unresectable or metastatic breast cancer [ID6348]
Technology appraisal guidance
TBC
Datopotamab deruxtecan for treating advanced non-small-cell lung cancer after platinum-based chemotherapy [ID6241]
Technology appraisal guidance
13 August 2025
DCVax-L for treating glioblastoma [ID836]
Technology appraisal guidance
TBC
Degarelix before or with radiotherapy for treating high-risk localised and locally advanced hormone-dependent prostate cancer [ID6419]
Technology appraisal guidance
TBC
Delandistrogene moxeparvovec for treating Duchenne muscular dystrophy in children 4 to 7 years ID3897
Technology appraisal guidance
TBC
Delgocitinib for treating moderate to severe chronic hand eczema ID6408
Technology appraisal guidance
TBC
Dexmedetomidine for treating agitation associated with bipolar disorder in people 18 to 75 years [TS ID 10725]
Technology appraisal guidance
TBC
Dexmedetomidine for treating agitation associated with schizophrenia TS ID 10726
Technology appraisal guidance
TBC
Diabetic retinopathy - ruboxistaurin [ID382]
Technology appraisal guidance
TBC
Donanemab for treating mild cognitive impairment or mild dementia caused by Alzheimer's disease [ID6222]
Technology appraisal guidance
26 March 2025
Dostarlimab with platinum-based chemotherapy for advanced or recurrent endometrial cancer with microsatellite stability or mismatch repair proficiency ID6415
Technology appraisal guidance
10 September 2025
Doxorubicin nanoparticles for previously treated advanced hepatocellular carcinoma [ID1314]
Technology appraisal guidance
TBC
Dupilumab for treating chronic spontaneous urticaria in people 12 years and over [ID4055]
Technology appraisal guidance
TBC
Dupilumab for treating moderate to severe chronic obstructive pulmonary disease ID6235
Technology appraisal guidance
TBC
Dupilumab for treating severe chronic rhinosinusitis with nasal polyposis (Review of TA648) [ID6480]
Technology appraisal guidance
11 September 2025
Durvalumab for adjuvant treatment of resectable non-small-cell lung cancer [ID1263]
Technology appraisal guidance
TBC
Durvalumab for treating limited-stage small-cell lung cancer after chemoradiation ID5073
Technology appraisal guidance
23 July 2025
Durvalumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer [ID6220]
Technology appraisal guidance
TBC
Durvalumab with concurrent chemoradiation for treating unresectable locally advanced non-small-cell lung cancer [ID3906]
Technology appraisal guidance
TBC
Durvalumab with platinum-based chemotherapy, then with or without olaparib, for treating newly diagnosed advanced or recurrent endometrial cancer ID6317
Technology appraisal guidance
21 May 2025
Durvalumab with tremelimumab for untreated advanced or unresectable hepatocellular carcinoma [ID2725]
Technology appraisal guidance
26 March 2025
Efanesoctocog alfa for treating and preventing bleeding episodes in haemophilia A [ID6170]
Technology appraisal guidance
TBC
Efgartigimod for treating generalised myasthenia gravis [ID4003]
Technology appraisal guidance
TBC
Efgartigimod with recombinant human hyaluronidase PH20 for treating chronic inflammatory demyelinating polyneuropathy ID6409
Technology appraisal guidance
TBC
Eflornithine for treating high-risk neuroblastoma with complete or partial response after immunotherapy [ID4060]
Technology appraisal guidance
25 June 2025
Elacestrant for treating oestrogen receptor-positive, HER2-negative advanced breast cancer with an ESR1 mutation after at least 1 endocrine treatment [ID6225]
Technology appraisal guidance
TBC
Elranatamab for treating relapsed and refractory multiple myeloma after 3 or more treatments [ID4026]
Technology appraisal guidance
11 December 2024
Empagliflozin for preventing cardiovascular events after acute myocardial infarction [ID6240]
Technology appraisal guidance
TBC
Encorafenib with binimetinib for treating BRAF V600E mutation-positive advanced non-small-cell lung cancer [ID6177]
Technology appraisal guidance
23 July 2025
Enfortumab vedotin for treating locally advanced or metastatic urothelial cancer after 2 therapies [ID3845]
Technology appraisal guidance
15 June 2022
Enfortumab vedotin with pembrolizumab for first-line treatment of unresectable or metastatic urothelial cancer who are eligible for platinum-containing chemotherapy [ID6332]
Technology appraisal guidance
4 June 2025
Epcoritamab for treating relapsed or refractory follicular lymphoma ID6338
Technology appraisal guidance
TBC
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