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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
Lurbinectedin for treating advanced small-cell lung cancer on or after platinum-based chemotherapy [ID3872]
Technology appraisal guidance
TBC
Maralixibat for treating cholestatic pruritus in Alagille syndrome [ID3941]
Technology appraisal guidance
22 January 2025
Maralixibat for treating progressive familial intrahepatic cholestasis [ID3818]
Technology appraisal guidance
TBC
Marstacimab for treating severe haemophilia A or severe haemophilia B in people 12 years and over [ID6342]
Technology appraisal guidance
26 February 2025
Masitinib with riluzole for treating amyotrophic lateral sclerosis ID6257
Technology appraisal guidance
TBC
Melanoma (metastatic) - talimogene laherparepvec [ID508]
Technology appraisal guidance
28 September 2016
Mirikizumab for treating moderately to severely active Crohn's disease [ID6244]
Technology appraisal guidance
TBC
Mirvetuximab soravtansine for previously treated platinum-resistant FR-alpha positive ovarian cancer [ID1527]
Technology appraisal guidance
TBC
Mirvetuximab soravtansine for treating folate receptor alpha-positive platinum-resistant advanced epithelial ovarian, fallopian tube or primary peritoneal cancer ID6442
Technology appraisal guidance
TBC
Molnupiravir for treating COVID 19 [ID6340]
Technology appraisal guidance
29 January 2025
MTX110 for untreated diffuse intrinsic pontine glioma [ID2695]
Technology appraisal guidance
TBC
Multiple sclerosis (relapsing, remitting, highly active) - natalizumab and Tyruko (natalizumab biosimilar) (after disease modifying therapy) [ID6369]
Technology appraisal guidance
16 July 2025
Navitoclax with ruxolitinib for treating myelofibrosis when stem cell transplant is unsuitable [ID5096]
Technology appraisal guidance
TBC
Nemolizumab for treating moderate to severe atopic dermatitis in people 12 years and over ID6221
Technology appraisal guidance
21 May 2025
Nemolizumab for treating prurigo nodularis [ID6451]
Technology appraisal guidance
21 May 2025
Neuroendocrine tumours (metastatic, unresectable, progressive) - everolimus and sunitinib [ID858]
Technology appraisal guidance
28 June 2017
Nintedanib for treating fibrosing interstitial lung disease in people aged 6 to 17 [ID6194]
Technology appraisal guidance
TBC
Nivolumab as neoadjuvant (with chemotherapy) and adjuvant (as monotherapy) treatment for resectable non-small-cell lung cancer [ID6310]
Technology appraisal guidance
TBC
Nivolumab for adjuvant treatment of high-risk hepatocellular carcinoma after liver resection or ablation [ID3858]
Technology appraisal guidance
17 July 2024
Nivolumab for adjuvant treatment of localised renal cell carcinoma [ID6362]
Technology appraisal guidance
TBC
Nivolumab for adjuvant treatment of resected non-small-cell lung cancer [ID4053]
Technology appraisal guidance
TBC
Nivolumab with chemotherapy for untreated unresectable or metastatic urothelial cancer [ID5102]
Technology appraisal guidance
TBC
Nivolumab with ipilimumab for untreated metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency [ID1136]
Technology appraisal guidance
TBC
Nivolumab with ipilimumab for untreated unresectable metastatic oesophageal squamous cell carcinoma ID1629
Technology appraisal guidance
TBC
Nivolumab with ipilimumab for untreated unresectable or metastatic urothelial cancer when cisplatin is unsuitable [ID3939]
Technology appraisal guidance
TBC
Nivolumab with ipilimumab for untreated unresectable stage 3 non-small-cell lung cancer [ID6248]
Technology appraisal guidance
TBC
Nusinersen and risdiplam for treating spinal muscular atrophy (review of TA588 and TA755) [ID6195]
Technology appraisal guidance
TBC
NY-ESO-1 T-cells for treating synovial sarcoma ID1286
Technology appraisal guidance
TBC
Obecabtagene autoleucel for treating relapsed or refractory B-cell acute lymphoblastic leukaemia [ID6347]
Technology appraisal guidance
25 June 2025
Obeticholic acid for treating liver fibrosis in people with steatohepatitis [ID1645]
Technology appraisal guidance
TBC
Odevixibat for treating cholestasis and pruritus in Alagille Syndrome [ID6181]
Technology appraisal guidance
TBC
Olaparib for treating BRCA mutation-positive HER2-negative metastatic breast cancer after chemotherapy (Review of TA762) [ID6336]
Technology appraisal guidance
TBC
Olaparib with cediranib for treating platinum-resistant recurrent ovarian cancer after 1 or 2 therapies [ID4065]
Technology appraisal guidance
TBC
Omaveloxolone for treating Friedreich's ataxia in people 16 years and over ID6423
Technology appraisal guidance
13 August 2025
Omburtamab for treating relapsed neuroblastoma [ID1664]
Technology appraisal guidance
TBC
Oral paclitaxel with encequidar for treating advanced breast cancer [ID5111]
Technology appraisal guidance
TBC
OrganOx metra for liver transplant [ID5116]
Technology appraisal guidance
TBC
Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection (Review of TA761) [ID5120]
Technology appraisal guidance
TBC
Osimertinib for maintenance treatment of EGFR mutation-positive locally advanced unresectable non-small-cell lung cancer after platinum-based chemoradiation [ID6223]
Technology appraisal guidance
20 August 2025
Osimertinib with pemetrexed and platinum-based chemotherapy for untreated EGFR mutation-positive advanced non-small-cell lung cancer [ID6328]
Technology appraisal guidance
TBC
Oxybutynin hydrochloride for managing neurogenic detrusor overactivity in people 6 years and over with spinal cord injury or spina bifida [ID5089]
Technology appraisal guidance
TBC
Palbociclib with trastuzumab and endocrine therapy for maintenance treatment of hormone-receptor positive, HER2-positive metastatic breast cancer [ID6251]
Technology appraisal guidance
TBC
Palforzia for treating peanut allergy in children aged 1 to 3 [ID6144]
Technology appraisal guidance
TBC
Palopegteriparatide for treating chronic hypoparathyroidism [ID6380]
Technology appraisal guidance
16 July 2025
Pegcetacoplan for amyotrophic lateral sclerosis TS ID 10594
Technology appraisal guidance
TBC
Pegcetacoplan for treating geographic atrophy [ID4041]
Technology appraisal guidance
TBC
Pegylated liposomal irinotecan in combination for untreated metastatic pancreatic cancer [ID6461]
Technology appraisal guidance
TBC
Pembrolizumab for adjuvant treatment of locally advanced cutaneous squamous cell carcinoma after surgery and radiotherapy ID 6473
Technology appraisal guidance
TBC
Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer [ID3907]
Technology appraisal guidance
11 December 2024
Pembrolizumab with chemoradiation for untreated high-risk locally advanced cervical cancer [ID6138]
Technology appraisal guidance
TBC
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