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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
Targeted-release budesonide for treating primary IgA nephropathy (review of TA937) [ID6485]
Technology appraisal guidance
17 December 2025
Tarlatamab for previously treated advanced small-cell lung cancer [ID6364]
Technology appraisal guidance
6 August 2025
Taselisib for previously treated ER-positive, HER2-negative, PIK3CA-positive breast cancer in postmenopausal women ID1401
Technology appraisal guidance
TBC
Telisotuzumab vedotin for treating c-MET overexpressed, EGFR wild-type, non-squamous advanced non-small-cell lung cancer after 1 or more systemic treatments [ID6253]
Technology appraisal guidance
TBC
Teplizumab for delaying the onset of stage 3 type 1 diabetes in people 8 years and over with stage 2 type 1 diabetes [ID6259]
Technology appraisal guidance
16 July 2025
Teprotumumab for treating thyroid eye disease [ID6432]
Technology appraisal guidance
13 August 2025
Third molars (impacted) - prophylactic removal [ID898]
Technology appraisal guidance
TBC
Tislelizumab for treating advanced non-small-cell lung cancer after platinum-based chemotherapy ID6161
Technology appraisal guidance
TBC
Tislelizumab with chemotherapy for untreated advanced oesophageal squamous cell cancer ID5113
Technology appraisal guidance
TBC
Tisotumab vedotin for treating recurrent or metastatic cervical cancer after chemotherapy ID3753
Technology appraisal guidance
TBC
Tolebrutinib for treating secondary progressive multiple sclerosis ID6351
Technology appraisal guidance
TBC
Topical rapamycin for treating facial angiofibromas associated with tuberous sclerosis complex in people 6 years and over [ID6391]
Technology appraisal guidance
TBC
Trastuzumab deruxtecan for treating HER2-positive unresectable or metastatic breast cancer after 1 or more anti-HER2 treatments [ID6309]
Technology appraisal guidance
TBC
Treatments for non-small-cell lung cancer [ID6234]
Technology appraisal guidance
TBC
Triheptanoin for treating long-chain fatty acid oxidation disorders [ID3891]
Technology appraisal guidance
TBC
Tucatinib with trastuzumab emtansine for treating HER2-positive unresectable or advanced breast cancer after a taxane, trastuzumab or both together [ID6165]
Technology appraisal guidance
TBC
Tucatinib with trastuzumab for previously treated HER2-positive colorectal cancer [ID6227]
Technology appraisal guidance
TBC
Upadacitinib for treating giant cell arteritis [ID6299]
Technology appraisal guidance
25 February 2026
Vanzacaftor–tezacaftor–deutivacaftor for treating cystic fibrosis with 1 or more F508del mutations in the CFTR gene in people aged 6 years and over [ID6372]
Technology appraisal guidance
21 August 2025
Veliparib with carboplatin and paclitaxel for untreated non-squamous non-small-cell lung cancer [ID1277]
Technology appraisal guidance
TBC
Venetoclax with azacitidine for untreated high-risk myelodysplastic syndromes [ID6314]
Technology appraisal guidance
TBC
Venetoclax with obinutuzumab for untreated chronic lymphocytic leukaemia when there is no 17p deletion or TP53 mutation and FCR (fludarabine, cyclophosphamide, rituximab) or BR (bendamustine, rituximab) are suitable (MA partial review of TA663) [ID6291]
Technology appraisal guidance
11 March 2026
Venglustat for treating gangliosidoses in people 2 years and over ID 6358
Technology appraisal guidance
TBC
Vepdegestrant for treating hormone receptor-positive HER2-negative metastatic breast cancer after endocrine treatment [ID6360]
Technology appraisal guidance
TBC
Vibostolimab–pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer [ID6382]
Technology appraisal guidance
TBC
Vimseltinib for treating tenosynovial giant cell tumours when surgery is unsuitable TSID 12099
Technology appraisal guidance
TBC
Vocimagene amiretrorepvec with extended-release 5-fluorocytosine for treating recurrent high-grade glioma [ID1425]
Technology appraisal guidance
TBC
Vorasidenib for treating astrocytoma or oligodendroglioma with IDH1 or IDH2 mutations after surgery in people 12 years and over [ID6407]
Technology appraisal guidance
10 September 2025
Vosoritide for treating achondroplasia in people 4 months and over ID6488
Technology appraisal guidance
TBC
Vutrisiran for treating transthyretin-related amyloidosis cardiomyopathy [ID6470]
Technology appraisal guidance
28 January 2026
Waldenstrom's macroglobulinaemia - ibrutinib [ID884]
Technology appraisal guidance
22 November 2017
Xevinapant with platinum-based chemotherapy and radiotherapy for untreated locally advanced squamous cell head and neck cancer [ID6199]
Technology appraisal guidance
TBC
Zanidatamab for treating HER2-positive advanced biliary tract cancer after 1 or more systemic treatments [ID6388]
Technology appraisal guidance
14 May 2026
Zanubrutinib for treating relapsed or refractory mantle cell lymphoma after 1 or more treatments [ID6392]
Technology appraisal guidance
TBC
Zanubrutinib for untreated chronic lymphocytic leukaemia [ID5079]
Technology appraisal guidance
TBC
Zilucoplan for treating antibody positive generalised myasthenia gravis [ID4008]
Technology appraisal guidance
TBC
Zuranolone for treating postnatal depression [ID6431]
Technology appraisal guidance
15 October 2025
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