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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
Spesolimab for preventing generalised pustular psoriasis flares in people 12 years and over [TSID12086]
Technology appraisal guidance
TBC
Sugemalimab with chemotherapy for untreated metastatic non-small-cell lung cancer [ID4001]
Technology appraisal guidance
TBC
Tafasitamab with lenalidomide and R-CHOP for untreated high-intermediate-risk or high-risk diffuse large B-cell lymphoma [ID6568]
Technology appraisal guidance
10 June 2027
Tafasitamab with lenalidomide and rituximab for treating relapsed or refractory follicular lymphoma after 1 or more systemic treatments ID6413
Technology appraisal guidance
15 July 2026
Talacotuzumab for untreated acute myeloid leukaemia [ID1262]
Technology appraisal guidance
TBC
Talazoparib with enzalutamide for untreated hormone-relapsed metastatic prostate cancer [ID4004]
Technology appraisal guidance
11 February 2026
Tarlatamamb for treating extensive stage small-cell lung cancer that has progressed after platinum-based chemotherapy [ID6617]
Technology appraisal guidance
TBC
Taselisib for previously treated ER-positive, HER2-negative, PIK3CA-positive breast cancer in postmenopausal women ID1401
Technology appraisal guidance
TBC
Teclistamab with daratumumab for treating relapsed or refractory multiple myeloma after 1 or more therapies [ID6201]
Technology appraisal guidance
28 July 2027
Telisotuzumab vedotin for treating c-MET overexpressed, EGFR wild-type, non-squamous advanced non-small-cell lung cancer after 1 or more systemic treatments [ID6253]
Technology appraisal guidance
TBC
Teplizumab for delaying the onset of stage 3 type 1 diabetes in people 8 years and over with stage 2 type 1 diabetes [ID6259]
Technology appraisal guidance
8 April 2026
Teprotumumab for treating thyroid eye disease [ID6432]
Technology appraisal guidance
TBC
Tezepelumab for treating severe chronic rhinosinusitis with nasal polyps ID6379
Technology appraisal guidance
9 September 2026
Third molars (impacted) - prophylactic removal [ID898]
Technology appraisal guidance
TBC
Tiragolumab with atezolizumab and bevacizumab for untreated unresectable or advanced hepatocellular carcinoma [TSID12238]
Technology appraisal guidance
TBC
Tiragolumab with atezolizumab for treating advanced oesophageal squamous cell cancer after chemoradiotherapy [ID6267]
Technology appraisal guidance
TBC
Tiragolumab with atezolizumab for treating locally advanced unresectable stage 3 non-small-cell lung cancer after at least 2 cycles of platinum-based chemoradiation [ID6250]
Technology appraisal guidance
TBC
Tiragolumab with atezolizumab for untreated PD-L1-positive advanced non-small-cell lung cancer [ID5122]
Technology appraisal guidance
TBC
Tislelizumab with chemotherapy for untreated advanced oesophageal squamous cell cancer [ID5113]
Technology appraisal guidance
TBC
Tislelizumab with chemotherapy for untreated unresectable or metastatic gastric or gastro-oesophageal junction cancer [ID6157]
Technology appraisal guidance
TBC
Tislelizumab with platinum-based chemotherapy and etoposide for untreated extensive-stage small-cell lung cancer [ID6158]
Technology appraisal guidance
TBC
Tisotumab vedotin for treating recurrent or metastatic cervical cancer that has progressed on or after systemic treatment [ID3753]
Technology appraisal guidance
12 June 2026
Tolebrutinib for treating non-relapsing secondary progressive multiple sclerosis ID6351
Technology appraisal guidance
TBC
Topical rapamycin for treating facial angiofibromas associated with tuberous sclerosis complex in people 6 years and over [ID6391]
Technology appraisal guidance
TBC
Toripalimab with chemotherapy for untreated recurrent or metastatic nasopharyngeal cancer ID6406
Technology appraisal guidance
2 December 2026
Tovorafenib for treating relapsed or refractory paediatric low-grade glioma with BRAF fusion or rearrangement or BRAF V600 mutation in people 6 months and over ID6557
Technology appraisal guidance
TBC
Trastuzumab deruxtecan for adjuvant treatment of high-risk HER2-positive residual invasive breast cancer after neoadjuvant chemotherapy [ID6509]
Technology appraisal guidance
TBC
Trastuzumab deruxtecan for treating HER2-positive unresectable or metastatic breast cancer after 1 or more anti-HER2 therapies (MA review TA704 and TA862) [ID5121]
Technology appraisal guidance
7 May 2026
Trastuzumab deruxtecan for treating HER2-positive unresectable or metastatic breast cancer after 1 or more anti-HER2 treatments [ID6309]
Technology appraisal guidance
TBC
Triheptanoin for treating long-chain fatty acid oxidation disorders [ID3891]
Technology appraisal guidance
TBC
Tucatinib with trastuzumab for previously treated HER2-positive colorectal cancer [ID6227]
Technology appraisal guidance
TBC
Upadacitinib for treating giant cell arteritis [ID6299]
Technology appraisal guidance
TBC
Veliparib with carboplatin and paclitaxel for untreated non-squamous non-small-cell lung cancer [ID1277]
Technology appraisal guidance
TBC
Venetoclax with azacitidine for treating acute myeloid leukaemia before and after an allogeneic stem cell transplant [ID6468]
Technology appraisal guidance
TBC
Venetoclax with azacitidine for untreated high-risk myelodysplastic syndromes [ID6314]
Technology appraisal guidance
TBC
Venetoclax with ibrutinib for treating relapsed mantle cell lymphoma [ID3879]
Technology appraisal guidance
TBC
Vepdegestrant for treating hormone receptor-positive HER2-negative metastatic breast cancer after endocrine treatment [ID6360]
Technology appraisal guidance
TBC
VER-01 for treating chronic low back pain [ID6638]
Technology appraisal guidance
TBC
Vibostolimab–pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer [ID6382]
Technology appraisal guidance
TBC
Vimseltinib for treating tenosynovial giant cell tumours when surgery is unsuitable TSID 12099
Technology appraisal guidance
TBC
Vocimagene amiretrorepvec with extended-release 5-fluorocytosine for treating recurrent high-grade glioma [ID1425]
Technology appraisal guidance
TBC
Vorasidenib for treating astrocytoma or oligodendroglioma with IDH1 or IDH2 mutations after surgery in people 12 years and over [ID6407]
Technology appraisal guidance
29 April 2026
Vosoritide for treating achondroplasia in people 4 months and over [ID6488]
Technology appraisal guidance
TBC
Waldenstrom's macroglobulinaemia - ibrutinib [ID884]
Technology appraisal guidance
22 November 2017
Xevinapant with platinum-based chemotherapy and radiotherapy for untreated locally advanced squamous cell head and neck cancer [ID6199]
Technology appraisal guidance
TBC
Zanidatamab for treating HER2-positive advanced biliary tract cancer after 1 or more systemic treatments [ID6388]
Technology appraisal guidance
TBC
Zanubrutinib for untreated chronic lymphocytic leukaemia [ID5079]
Technology appraisal guidance
TBC
Zilucoplan for treating antibody positive generalised myasthenia gravis [ID4008]
Technology appraisal guidance
TBC
Zuranolone for treating postnatal depression [ID6431]
Technology appraisal guidance
TBC
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