Research recommendation(s) from an individual piece of guidance Guidance: Laparoscopic gastric plication for the treatment of severe obesity Date issued: 27 November 2012 Research recommendations coming out of this guidance NICE encourages further research on laparoscopic gastric plication for severe obesity, which should include information about long-term efficacy and safety, and specifically how the procedure influences further gastric surgery. Comparison with alternative procedures would be useful.