Research recommendation(s) from an individual piece of guidance Guidance: Radiofrequency cold ablation for respiratory papillomatosis Date issued: 27 November 2012 Research recommendations coming out of this guidance NICE encourages further research and data collection on radiofrequency cold ablation for respiratory papillomatosis. In particular, research and data collection should report treatment indication (whether for primary or secondary treatment of respiratory papillomatosis), outcomes related to timing and site of disease recurrence, the need for tracheostomy after the procedure, and longer-term survival. In addition, any effect of the procedure on voice quality should be documented.