Research recommendation(s) from an individual piece of guidance Guidance: Irreversible electroporation for treating primary lung cancer and metastases in the lung Date issued: 23 February 2013 Research recommendations coming out of this guidance Current evidence on the safety and efficacy of irreversible electroporation for treating primary lung cancer and metastases in the lung is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research. In particular, studies should report the effect of the procedure on local tumour control and patient survival.