Research recommendation(s) from an individual piece of guidance Guidance: Endoscopic thoracic sympathectomy for primary hyperhidrosis of the upper limb Date issued: 27 May 2014 Research recommendations coming out of this guidance Further research into efficacy and safety of endoscopic thoracic sympathectomy (ETS) for primary hyperhidrosis of the upper limb should include clear information on patient selection and should seek to identify which patient characteristics might predict severe side effects. All complications should be reported. Outcomes should include measurements of efficacy, including quality of life and social functioning both in the short and long term and in particular the frequency and severity of compensatory hyperhidrosis.