1.1
The evidence on ultrasound‑enhanced, catheter‑directed thrombolysis for pulmonary embolism raises no major safety concerns over those of catheter‑directed thrombolysis (CDT) alone. With regard to efficacy, evidence of any enhancement of thrombolysis over CDT alone is inadequate in quality and quantity. Therefore, this procedure should only be used with special arrangements for clinical governance, consent and audit or research.