Research recommendation(s) from an individual piece of guidance Guidance: Miniature lens system implantation for advanced age-related macular degeneration Date issued: 28 September 2016 Research recommendations coming out of this guidance NICE encourages further research and publication on efficacy of miniature lens system implantation for advanced age-related macular degeneration (AMD) which patients may benefit and on safety and efficacy outcomes, particularly longer-term results. NICE may update the guidance on publication of further evidence.