Research recommendation(s) from an individual piece of guidance Guidance: Artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure Date issued: 20 December 2017 Research recommendations coming out of this guidance NICE encourages further research into total artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure, including well matched comparative studies. NICE may update the guidance on publication of further evidence.