Research recommendation(s) from an individual piece of guidance Guidance: Low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures Date issued: 31 July 2018 Research recommendations coming out of this guidance NICE encourages further research into low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures. Further research should include details of patient selection, fracture site, and risk factors and comorbidities that delay fracture healing.