Research recommendation(s) from an individual piece of guidance Guidance: Endovascular insertion of an intrasaccular wire-mesh blood-flow disruption device for intracranial aneurysms Date issued: 14 August 2019 Research recommendations coming out of this guidance Current evidence on the safety and efficacy of endovascular insertion of an intrasaccular wire-mesh blood-flow disruption device for intracranial aneurysms is adequate to support the use of this procedure provided that standard arrangements are in place for clinical governance, consent and audit.