NICE may update this guidance after 3 years or sooner if important new information becomes available, including evidence on:
- the epidemiology of CJD, including data on the prevalence of CJD and its infectivity in the UK population
- the transmission of CJD by surgical instruments, including cases of CJD in which surgery is a possible route of transmission
- the cost effectiveness of single-use instruments for use in interventional procedures on high-risk tissues
- commercially available decontmination methods that are safe and cost effective against prions
- the systems for, and cost effectiveness of, maintaining set integrity and traceability of instruments.