Research recommendations coming out of this guidance What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination with a chlorhexidine body wash in the whole population? Does the use of barbed sutures for wound closure reduce the incidence of surgical site infection? Which closure method or technique is the most effective for reducing surgical site infections in patients undergoing emergency surgery? Is the use of chlorhexidine body wash associated with increased antimicrobial resistance? What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in the prevention of surgical site infection when applied to the skin before incision? Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically and cost effective in reducing surgical site infection rates? Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated or triclosan-impregnated sutures? What is the contribution to clinical effectiveness of the timing of nasal decolonisation and body wash for the prevention of surgical site infection? What is the effectiveness of decolonisation using alternative interventions in combination with nasal decolonisation in the prevention of surgical site infections when chlorhexidine is contraindicated? What is the clinical and cost effectiveness of a double application of antiseptic to the skin at the surgical site compared with a single application? What is the clinical and cost effectiveness of different modes of applying skin antiseptic before incision in the prevention of surgical site infection?
What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination with a chlorhexidine body wash in the whole population?
Which closure method or technique is the most effective for reducing surgical site infections in patients undergoing emergency surgery?
What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in the prevention of surgical site infection when applied to the skin before incision?
Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically and cost effective in reducing surgical site infection rates?
Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated or triclosan-impregnated sutures?
What is the contribution to clinical effectiveness of the timing of nasal decolonisation and body wash for the prevention of surgical site infection?
What is the effectiveness of decolonisation using alternative interventions in combination with nasal decolonisation in the prevention of surgical site infections when chlorhexidine is contraindicated?
What is the clinical and cost effectiveness of a double application of antiseptic to the skin at the surgical site compared with a single application?
What is the clinical and cost effectiveness of different modes of applying skin antiseptic before incision in the prevention of surgical site infection?