Crohn’s disease: management

Full guideline – October 2012

NICE's original guidance on Crohn's disease: management in adults, children and young people was published in October 2012; it was partially updated in May 2016 when a new recommendation on inducing remission was added. It has now undergone a further partial update published in May 2019. The full, current recommendations can be found on the NICE website.

This document preserves evidence reviews and committee discussions for areas of the guideline that have not been updated in 2019. Black shading indicates text from 2012 replaced by the 2019 update.

• Download full guideline
• Addendum May 2016

The following appendix files have also been updated in May 2019:

• Review protocols
• Search strategies
• Excluded studies
• Evidence tables
• Forest plots
• Sift audit

The following appendix files are from the original 2012 guideline and have not been updated:

• Scope
• Declarations of interest
• Health economics report
• Research recommendations
• Review of Cochrane ASA review
• 5-ASA call for evidence
• 5-ASA adverse-event data
• Immunosuppressive safety data
• Surgery recurrence rates
• Stricture management data
• Patient information themes