Research recommendation(s) from an individual piece of guidance
- Guidance:
- Thyroid disease: assessment and management
- Date issued:
Research recommendations coming out of this guidance
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What is the clinical and cost effectiveness of levothyroxine (T4) and liothyronine (T3) combination therapy compared with T4 alone for people with hypothyroidism whose symptoms have not responded sufficiently to T4 alone? Does DiO2 polymorphism affect the response to combination therapy with T4 and T3?
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What is the clinical and cost effectiveness of iodine for people with subclinical hypothyroidism?
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What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism?
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What is the clinical and cost effectiveness of treatment (antithyroid drugs or radioactive iodine) for improving long-term health outcomes for people with subclinical hyperthyroidism?
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Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid drugs?
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What is the long-term clinical and cost effectiveness, including safety, of radioactive iodine for hyperthyroidism?
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What is the clinical and cost effectiveness of dosimetry-guided radioactive iodine strategies for hyperthyroidism?
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What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for people with T3 thyrotoxicosis due to Graves' disease?
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What is the clinical and cost effectiveness of levothyroxine for people under 65 with symptomatic subclinical hypothyroidism?
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What is the clinical and cost effectiveness of a block and replace regimen compared with a titration regimen of antithyroid drugs for Graves' disease?
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What is the clinical and cost effectiveness of percutaneous thermal ablation for benign thyroid nodules?