Major trauma: assessment and initial management

Research recommendation(s) from an individual piece of guidance

Guidance:

Major trauma: assessment and initial management

Date issued:

17 February 2016

Research recommendations coming out of this guidance

• Point-of-care coagulation testing:- What is the clinical and cost effectiveness of point-of-care coagulation testing using rotational thromboelastometry (ROTEM) or thromboelastography (TEG) to target treatment, compared with standard laboratory coagulation testing?

• Lactate level for monitoring severity of shock:- Is lactate monitoring in patients with major trauma clinically and cost effective?

• Morphine compared with ketamine for first-line management of pain:- Is morphine clinically and cost effective compared with ketamine for first-line pharmacological pain management (in both pre-hospital and hospital settings) in patients with major trauma?