Research recommendations coming out of this guidance Point-of-care coagulation testing:- What is the clinical and cost effectiveness of point-of-care coagulation testing using rotational thromboelastometry (ROTEM) or thromboelastography (TEG) to target treatment, compared with standard laboratory coagulation testing? Lactate level for monitoring severity of shock:- Is lactate monitoring in patients with major trauma clinically and cost effective? Morphine compared with ketamine for first-line management of pain:- Is morphine clinically and cost effective compared with ketamine for first-line pharmacological pain management (in both pre-hospital and hospital settings) in patients with major trauma?
Point-of-care coagulation testing:- What is the clinical and cost effectiveness of point-of-care coagulation testing using rotational thromboelastometry (ROTEM) or thromboelastography (TEG) to target treatment, compared with standard laboratory coagulation testing?
Lactate level for monitoring severity of shock:- Is lactate monitoring in patients with major trauma clinically and cost effective?
Morphine compared with ketamine for first-line management of pain:- Is morphine clinically and cost effective compared with ketamine for first-line pharmacological pain management (in both pre-hospital and hospital settings) in patients with major trauma?