| Balloon dilation for chronic eustachian tube dysfunction | IPG665 | | |
| Cannabidiol with clobazam for treating seizures associated with Dravet syndrome | TA614 | | |
| Cannabidiol with clobazam for treating seizures associated with Lennox–Gastaut syndrome | TA615 | | |
| PulmoVista 500 for monitoring ventilation in critical care | MIB203 | | |
| LQD Spray for treating acute and chronic wounds | MIB202 | | |
| Lung cancer in adults | QS17 | | |
| eXroid for internal haemorrhoids | MIB201 | | |
| PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection | MIB200 | | |
| Optowire for measuring fractional flow reserve | MIB199 | | |
| gammaCore for cluster headache | MTG46 | | |
| Cerliponase alfa for treating neuronal ceroid lipofuscinosis type 2 | HST12 | | |
| Irreversible electroporation for primary liver cancer | IPG664 | | |
| Diverticular disease: diagnosis and management | NG147 | | |
| AmnioSense for unexplained vaginal wetness in pregnancy | MIB198 | | |
| Antimicrobial prescribing: meropenem with vaborbactam | ES21 | | |
| Workplace health: long-term sickness absence and capability to work | NG146 | | |
| Neratinib for extended adjuvant treatment of hormone receptor-positive, HER2-positive early stage breast cancer after adjuvant trastuzumab | TA612 | | |
| Rapid tests for group A streptococcal infections in people with a sore throat | DG38 | | |
| Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast | DG37 | | |
| Pentosan polysulfate sodium for treating bladder pain syndrome | TA610 | | |
| Ibrutinib with rituximab for treating Waldenstrom's macroglobulinaemia (terminated appraisal) | TA608 | | |
| Ramucirumab for treating unresectable hepatocellular carcinoma after sorafenib (terminated appraisal) | TA609 | | |
| Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management | CG184 | | |
| Rivaroxaban for preventing atherothrombotic events in people with coronary or peripheral artery disease | TA607 | | |
| Midcarpal hemiarthroplasty for wrist arthritis | IPG663 | | |
| End of life care for adults: service delivery | NG142 | | |
| Lanadelumab for preventing recurrent attacks of hereditary angioedema | TA606 | | |
| superDimension Navigation System to help diagnostic sampling of peripheral lung lesions | MIB194 | | |
| MR-proADM test for use with clinical deterioration scores in cases of suspected infection | MIB195 | | |
| Diabetic foot problems: prevention and management | NG19 | | |
| Voretigene neparvovec for treating inherited retinal dystrophies caused by RPE65 gene mutations | HST11 | | |
| Gastro-oesophageal reflux disease in children and young people: diagnosis and management | NG1 | | |
| Xeomin (botulinum neurotoxin type A) for treating chronic sialorrhoea | TA605 | | |
| EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing | MTG12 | | |
| Familial hypercholesterolaemia: identification and management | CG71 | | |
| Idelalisib for treating refractory follicular lymphoma | TA604 | | |
| Cellulitis and erysipelas: antimicrobial prescribing | NG141 | | |
| High-intensity focused ultrasound for glaucoma | IPG661 | | |
| Bioprosthetic plug insertion for anal fistula | IPG662 | | |
| Pomalidomide with bortezomib and dexamethasone for treating relapsed or refractory multiple myeloma (terminated appraisal) | TA602 | | |
| Lenalidomide with bortezomib and dexamethasone for untreated multiple myeloma (terminated appraisal) | TA603 | | |
| Tegaderm CHG securement dressing for vascular access sites in critically ill adults | MTG25 | | |
| Pneumonia (community-acquired): antimicrobial prescribing | NG138 | | |
| Pneumonia (hospital-acquired): antimicrobial prescribing | NG139 | | |
| Attention deficit hyperactivity disorder: diagnosis and management | NG87 | | |
| Implant insertion for prominent ears | IPG660 | | |
| InterDry for intertrigo | MIB192 | | |
| Suicide prevention | QS189 | | |
| SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea | MIB190 | | |
| Multiple pregnancy: twin and triplet pregnancies | QS46 | | |