Canagliflozin in combination therapy for treating type 2 diabetes

  • Technology appraisal guidance
  • TA315
  • Published: 
Download guidance (PDF)

7 Sources of evidence considered by the Committee

The Evidence Review Group (ERG) report for this appraisal was prepared by Southampton Health Technology Assessments Centre (SHTAC), University of Southampton:

  • Copley V, Pickett K, Shepherd J, et al. Canagliflozin in combination therapy for treating type 2 diabetes, December 2013

The following organisations accepted the invitation to participate in this appraisal as consultees and commentators. They were invited to comment on the draft scope, the ERG report and the appraisal consultation document (ACD). Manufacturers or sponsors were also invited to make written submissions. Professional or specialist and patient or carer groups, and other consultees, had the opportunity to give their expert views. Manufacturers or sponsors, professional or specialist and patient or carer groups, and other consultees, also have the opportunity to appeal against the final appraisal determination.

Manufacturers or sponsors:

  • Janssen

Professional or specialist and patient or carer groups:

  • Association of British Clinical Diabetologists

  • Diabetes UK

  • National Diabetes Nurse Consultant Group

  • Royal College of Nursing

  • Royal College of Physicians

Other consultees:

  • Department of Health

  • NHS England

  • Welsh Government

Commentator organisations (did not provide written evidence and without the right of appeal):

  • AstraZeneca

  • Boehringer Ingelheim

  • Commissioning Support Appraisal Service

  • Department of Health, Social Services and Public Safety for Northern Ireland

  • Eli Lilly UK

  • Healthcare Improvement Scotland

  • Medicines and Healthcare Products Regulatory Agency (MHRA)

  • Merck Sharp and Dohme

  • National Clinical Guidelines Centre

  • National Institute for Health Research Health Technology Assessment Programme

  • Novo Nordisk

  • Pfizer

  • Sanofi

  • Southampton Health Technology Assessments Centre (SHTAC), University of Southampton

The following individuals were selected from clinical specialist and patient expert nominations from the consultees and commentators. They gave their expert personal view on canagliflozin by attending the initial Committee discussion and providing written evidence to the Committee. They were also invited to comment on the ACD.

  • Professor David Matthews, Professor of Diabetes Medicine, nominated by an organisation representing Janssen – clinical specialist

  • Dr Thozhukat Sathyapalan, Reader and Honorary Consultant medical Consultant Endocrinologist, nominated by organisation representing Royal College of Physicians and Association of British Clinical Diabetologists – clinical specialist

Representatives from the following manufacturer or sponsor attended Committee meetings. They contributed only when asked by the Committee chair to clarify specific issues and comment on factual accuracy.

  • Janssen

ISBN 978-1-4731-0623-9