Draft guidance | Immunosuppressive therapy for kidney transplant in adults | Guidance

The Department of Health has asked the National Institute for Health and Care Excellence (NICE) to produce guidance on using immunosuppressive therapy for kidney transplant in adults, in the NHS in England. The appraisal committee has considered the evidence submitted and the views of non-company consultees and commentators, clinical experts and patient experts.

This document has been prepared for consultation with the consultees. It summarises the evidence and views that have been considered, and sets out the recommendations made by the committee. NICE invites comments from the consultees and commentators for this appraisal and the public. This document should be read along with the evidence (see the committee papers).

The appraisal committee is interested in receiving comments on the following:

Has all of the relevant evidence been taken into account?
Are the summaries of clinical and cost effectiveness reasonable interpretations of the evidence?
Are the recommendations sound and a suitable basis for guidance to the NHS?
Are there any aspects of the recommendations that need particular consideration to ensure we avoid unlawful discrimination against any group of people on the grounds of race, gender, disability, religion or belief, sexual orientation, age, gender reassignment, pregnancy and maternity?
Are there any outstanding clinical and commissioning issues that arise during immunosuppressive therapy for kidney transplant for which further guidance is needed? Is there sufficient evidence available that could support the development of additional technology appraisal recommendations to address these issues? Would additional NICE technology appraisal guidance add value, or would other routes be more appropriate to eliminate these issues, such as other NICE programmes or NHS England commissioning policies?

Note that this document is not NICE's final guidance on these technologies. The recommendations in section 1 may change after consultation.

After consultation:

The appraisal committee will meet again to consider the evidence, this appraisal consultation document and comments from the consultees.
At that meeting, the committee will also consider comments made by people who are not consultees.
After considering these comments, the committee will prepare the final appraisal determination.
Subject to any appeal by consultees, the final appraisal determination may be used as the basis for NICE’s guidance on using immunosuppressive therapy for kidney transplant in adults in the NHS in England.

For further details, see NICE’s guide to the processes of technology appraisal.