Final appraisal determination document (PDF 260 KB) Published: 17 September 2018 Committee papers (PDF 22.05 MB) Published: 17 September 2018 Public committee slides - clinical (PDF 565 KB) Published: 17 September 2018 Public committee slides - cost effectiveness (PDF 648 KB) Published: 17 September 2018 This page was last updated: 17 September 2018