This guidance has been partially updated by ‘Paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan for second-line or subsequent treatment of advanced ovarian cancer (review)’ (NICE technology appraisal guidance 91 [TA91]).

Recommendations 1.3, 1.4 and 1.5 of TA55 on re-challenge therapy and the second-line treatment of advanced ovarian cancer have been replaced. The recommendations for first-line treatment still stand. See TA91 (www.nice.org.uk/guidance/TA91) for details of the new recommendations and evidence considered.