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Guidance programme

Advice programme

Showing 4801 to 4815 of 7685 results

  1. NICE encourages further research into balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension. Details of patient selection, all complications, and subsequent treatments and interventions for pulmonary hypertension should be collected. Reports should include quality-of-life outcomes, long-term efficacy outcomes and survival. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG554/1 Question NICE encourages further research into balloon pulmonary angioplasty for chronic thromboembolic pulmonary

    Research recommendation
    Published
    4 May 2016

  2. NICE encourages further research into preoperative high dose rate brachytherapy for rectal cancer. Trials should be designed to provide clear data on the efficacy of this procedure, whether or not other adjunctive treatments are used. Research should document adjunctive treatments and details of patient selection. Outcomes should include local recurrence, survival, disease-free survival and quality of life. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG531/1 Question NICE encourages further research into preoperative high dose rate brachytherapy for rectal cancer.

    Research recommendation
    Published
    12 October 2015

  3. Newly diagnosed seizures (focal and generalised) – monotherapy: How do the newer AEDs compare in efficacy to the standard AEDs in the treatment of newly diagnosed epilepsy? Focal seizures: carbamazepine, eslicarbazepine acetate, lacosamide, lamotrigine, levetiracetam, pregabalin  and zonisamide. Generalised seizures: lamotrigine, levetiracetam, sodium valproate and zonisamide.

    Recommendation ID CG137/1 Question Newly diagnosed seizures (focal and generalised) – monotherapy: How do the newer AEDs compare in efficacy

    Research recommendation
    Published
    13 August 2021

  4. NICE encourages further research into ultrasound-enhanced, catheter-directedthrombolysis for pulmonary embolism. Ideally this should include comparative studies against catheter-directed thrombolysis alone. Patient selection should be  documented. The dose of thrombolytic agent used and the duration of thrombolysis should be reported, together with all complications. Outcome measures should include the success of thrombolysis (complete, partial or failed) and long-term sequelae. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG524/1 Question NICE encourages further research into ultrasound-enhanced, catheter-directedthrombolysis for pulmonary

    Research recommendation
    Published
    6 October 2015

  5. NICE encourages further research into radiofrequency ablation for gastric antral vascular ectasia and collaborative publication of data from local audit. Patient selection should be clearly documented, including details of prior treatments. Outcomes should include success and duration of effect in controlling bleeding and the effect of this on the need for blood transfusion. All complications should be reported. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG520/1 Question NICE encourages further research into radiofrequency ablation for gastric antral vascular ectasia and

    Research recommendation
    Published
    6 October 2015

  6. NICE encourages further research into CXL using riboflavin and UVA for keratoconus and keratectasia, especially epithelium-on (transepithelial) CXL and the combination (CXL-plus) procedures. Details of the techniques used should be clearly described. Reported outcomes should include visual acuity, corneal topography and quality of life. Data on long-term outcomes for all types of CXL using riboflavin and UVA for keratoconus and keratectasia would be useful – specifically data about prevention of progression to corneal transplantation and about repeat procedures and their efficacy.

    Recommendation ID IPG466/1 Question NICE encourages further research into CXL using riboflavin and UVA for keratoconus and keratectasia

    Research recommendation
    Published
    9 June 2015

  7. NICE recommends that robust evidence be generated to show the clinical effectiveness of pharmacokinetic dose adjustment of continuous infusion 5-FU in people with colorectal cancer.

    Recommendation ID DG16/2 Question NICE recommends that robust evidence be generated to show the clinical effectiveness of pharmacokinetic

    Research recommendation
    Published
    9 June 2015

  8. Non-invasive tests for diagnosing NAFLD and advanced liver fibrosis in children and young people:- Which non-invasive tests most accurately diagnose NAFLD and advanced liver fibrosis in children and young people?

    Recommendation ID NG49/3 Question Non-invasive tests for diagnosing NAFLD and advanced liver fibrosis in children and young people:- Which

    Research recommendation
    Published
    24 August 2016

  9. Non-invasive tests for diagnosing NAFLD in adults:- Which non-invasive tests are most accurate and cost-effective in identifying non-alcoholic fatty liver disease (NAFLD) in adults with risk factors, type 2 diabetes and metabolic syndrome?

    Recommendation ID NG49/1 Question Non-invasive tests for diagnosing NAFLD in adults:- Which non-invasive tests are most accurate and cost-effective

    Research recommendation
    Published
    24 August 2016

  10. Non-invasive tests for diagnosing NASH:- Which non-invasive tests most accurately identify non-alcoholic steatohepatitis (NASH) in people with non-alcoholic fatty liver disease (NAFLD)?

    Recommendation ID NG49/2 Question Non-invasive tests for diagnosing NASH:- Which non-invasive tests most accurately identify non-alcoholic

    Research recommendation
    Published
    24 August 2016

  11. What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared with continuous positive airways pressure (CPAP) flow driver as the primary mode of ventilation?

    Recommendation ID NG124/1 Question What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared

    Research recommendation
    Published
    16 August 2019

  12. Non-pharmacological interventions for patients with an acute painful sickle cell episode:- For patients with an acute painful sickle cell episode, are non-pharmacological interventions, such as massage, effective in improving their recovery from the episode?

    Recommendation ID CG143/4 Question Non-pharmacological interventions for patients with an acute painful sickle cell episode:- For patients

    Research recommendation
    Published
    9 June 2015

  13. What is the clinical and cost effectiveness of antibiotics for the management of acute diverticulitis in primary care?

    Recommendation ID NG147/1 Question What is the clinical and cost effectiveness of antibiotics for the management of acute diverticulitis

    Research recommendation
    Published
    10 February 2020

  14. Nutritional support after radical surgery:- What is the optimal method of delivering nutritional support to adults after surgery with curative intent for oesophago-gastric cancer?

    Recommendation ID NG83/3 Question Nutritional support after radical surgery:- What is the optimal method of delivering nutritional support

    Research recommendation
    Published
    13 November 2018

  15. Nutrition:- Does a high calorific diet prolong survival of people with motor neurone disease (MND) if initiated following diagnosis or following initiation of feeding using a gastrostomy?

    Recommendation ID NG42/5 Question Nutrition:- Does a high calorific diet prolong survival of people with motor neurone disease (MND) if

    Research recommendation
    Published
    21 March 2016