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Showing 4351 to 4365 of 7691 results

  1. Is the use of chlorhexidine body wash associated with increased antimicrobial resistance?

    Recommendation ID NG125/2 Question Is the use of chlorhexidine body wash associated with increased antimicrobial resistance? Any

    Research recommendation
    Published
    16 August 2019

  2. There is uncertainty about how much remote monitoring devices would affect resource use in the NHS and personal social services. Some impacts may not have been included in the external assessment group's (EAG) model because of a lack of data (see section 3.12 ), including resource use related to carers (see section 3.13 ). Adopting the technologies may change how care is provided (see section 3.4 ) so their effect on resources is hard to estimate without direct data. So, the committee recommended collecting data on how much using the devices affects resource use, to inform cost-effectiveness estimates. Data on time dedicated to training and spent reviewing device results should also be collected. The broader impact on services provided by Parkinson's specialist teams and carers should be considered.

    Recommendation ID DG51/01 Question There is uncertainty about how much remote monitoring devices would affect resource use in the NHS and

    Research recommendation
    Published
    7 March 2023

  3. What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination with a chlorhexidine body wash in the whole population?

    Recommendation ID NG125/1 Question What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination

    Research recommendation
    Published
    16 August 2019

  4. How much using remote monitoring devices to guide decisions about care affects symptoms, and therefore health-related quality of life, is uncertain. How long after using the devices any impact would last is also uncertain. This had a sizeable influence on cost-effectiveness estimates (see section 3.10 ). Data on this came from studies that did not represent likely NHS practice (see section 3.6 ), which is itself uncertain (see section 3.3 ), and from assumptions made by the EAG because of lack of data. For its model, the EAG used a published algorithm from Chandler et al. (2020) to estimate quality-adjusted life years (QALYs) from the Unified Parkinson's Disease Rating Scale (UPDRS) domain scores. The clinical experts said that health-related quality of life questionnaires like the PDQ‑39 are increasingly used in trials to assess health-related quality of life for people with Parkinson's disease. The committee also recognised that the effect of the devices on the health-related quality of life of carers had not been included in the EAG's model because of a lack of data (see section 3.13 ).

    Recommendation ID DG51/02 Question How much using remote monitoring devices to guide decisions about care affects symptoms, and therefore

    Research recommendation
    Published
    7 March 2023

  5. NICE concluded that the cost consequences of using HumiGard in abdominal surgery are very uncertain, and that further research is needed on resource use.

    Recommendation ID MTG31/2 Question NICE concluded that the cost consequences of using HumiGard in abdominal surgery are very uncertain

    Research recommendation
    Published
    26 April 2017

  6. More research is needed on the following artificial intelligence (AI)‑derived software to analyse chest X‑rays alongside clinician review for suspected lung cancer in adults referred from primary care:

    Recommendation ID HTE12/1 Question More research is needed on the following artificial intelligence (AI)‑derived software to analyse chest

    Research recommendation
    Published
    11 January 2024

  7. What is the contribution to clinical effectiveness of the timing of nasal decolonisation and body wash for the prevention of surgical site infection?

    Recommendation ID NG125/6 Question What is the contribution to clinical effectiveness of the timing of nasal decolonisation and body wash

    Research recommendation
    Published
    26 October 2020

  8. Is high-flow nasal oxygen effective in reducing breathlessness compared with standard care or conventional oxygen therapy for people in hospital with COVID-19 and respiratory failure when it is agreed that treatment will not be escalated beyond non-invasive respiratory support or palliative care is needed?

    Recommendation ID NG191/5 Question Is high-flow nasal oxygen effective in reducing breathlessness compared with standard care or conventional

    Research recommendation
    Published
    21 October 2021

  9. In people with high-risk non-muscle-invasive bladder cancer, are these follow-up regimens equally effective in terms of identification of progression, cost effectiveness and health-related quality of life? - Cystoscopic follow-up at 3, 6, 12, 18, 24, 36 and 48 months, and then annually, interspersed with non-invasive urinary tests. - Cystoscopic follow-up at 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42 and 48 months, and then annually thereafter.

    Recommendation ID NG2/3 Question In people with high-risk non-muscle-invasive bladder cancer, are these follow-up regimens equally effective

    Research recommendation
    Published
    9 June 2015

  10. Hysteroscopic removal of submucosal fibroids compared with other uterine-sparing treatments for HMB:- Is hysteroscopic removal of submucosal fibroids more effective and cost-effective than other uterine-sparing treatments for the management of HMB?

    Recommendation ID NG88/4 Question Hysteroscopic removal of submucosal fibroids compared with other uterine-sparing treatments for HMB:- Is

    Research recommendation
    Published
    14 November 2018

  11. Intra-aortic balloon counter‑pulsation: In people with acute heart failure and hypoperfusion syndrome, is the use of intra‑aortic balloon counter‑pulsation pump (IABP) better than the use of intravenous inotropes?

    Recommendation ID CG187/03 Question Intra-aortic balloon counter‑pulsation: In people with acute heart failure and hypoperfusion syndrome

    Research recommendation
    Published
    16 December 2021

  12. Vitamin D supplements in the management of CKD–mineral and bone disorders: In people with hyperparathyroidism secondary to CKD, does treatment with vitamin D or vitamin D analogues improve patient-related outcomes?

    Recommendation ID NG203/21 Question Vitamin D supplements in the management of CKD–mineral and bone disorders: In people with hyperparathyroidism

    Research recommendation
    Published
    30 September 2021

  13. Managing meningioma: immediate versus deferred radiotherapy for incompletely excised grade I meningioma:- Is immediate or deferred radiotherapy better for incompletely excised grade I meningioma?

    Recommendation ID NG99/5 Question Managing meningioma: immediate versus deferred radiotherapy for incompletely excised grade I meningioma:-

    Research recommendation
    Published
    11 December 2018

  14. What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment for adults with persistent nausea or vomiting not caused by chemotherapy which hasn't fully responded to optimised conventional antiemetics?

    Recommendation ID NG144/8 Question What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment

    Research recommendation
    Published
    10 February 2020

  15. Techniques for confirming a diagnosis in people with suspected atypical Spitzoid melanocytic lesions: In people with reported atypical Spitzoid lesions, how effective are fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH) and tests to detect driver mutations compared with histopathological examination alone in predicting disease specific survival? This should be investigated ina prospective diagnostic study. Secondary outcomes should include sensitivity, specificity, accuracy, positive predictive value, disease specific survival and progression free survival.

    Recommendation ID NG14/07 Question Techniques for confirming a diagnosis in people with suspected atypical Spitzoid melanocytic lesions:

    Research recommendation
    Published
    4 August 2022