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Area of interest

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Guidance programme

Advice programme

Showing 5641 to 5655 of 7679 results

  1. Further research is recommended to identify any health conditions or groups of patients that would benefit more from inhaled sedation with Sedaconda ACD-S than from standard care

    Recommendation ID MTG65/01 Question Further research is recommended to identify any health conditions or groups of patients that would

    Research recommendation
    Published
    1 February 2022

  2. Further research is recommended to resolve the uncertainties about the long-term clinical effectiveness of darvadstrocel compared with standard care. In particular, estimates of long-term remission rates (minimum of 2 years' follow-up) in Crohn's disease with perianal fistulas are needed.

    Recommendation ID TA556/1 Question Further research is recommended to resolve the uncertainties about the long-term clinical effectiveness

    Research recommendation
    Published
    19 March 2019

  3. Further research is recommended to resolve uncertainties about the clinical effectiveness of degarelix compared with luteinising hormone-releasing hormone (LHRH) agonists such as leuprorelin, goserelin and triptorelin for treating advanced hormone-dependent prostate cancer, particularly in subgroups of people with preexisting cardiovascular disease, people with skeletal (including spinal) metastases and people with impending ureteric and urethral obstruction. Research should be planned as part of well-conducted randomised clinical trials.

    Recommendation ID TA404/1 Question Further research is recommended to resolve uncertainties about the clinical effectiveness of degarelix

    Research recommendation
    Published
    17 October 2016

  4. Further research is recommended to resolve uncertainties about the cost effectiveness of fluocinolone acetonide intravitreal implant for the treatment of chronic diabetic macular oedema. This should focus on a group of patients whose condition is unresponsive to other available therapies, and include measures of efficacy and health-related quality of life. Research should focus on identifying appropriate utility values, taking into account the utility values for different levels of visual acuity and the relative relationship in utility values from treating the best-seeing and the worse-seeing eye. The appropriateness of generalising utility values from one group of eye conditions to another group would also be of value.

    Recommendation ID TA301/1 Question Further research is recommended to resolve uncertainties about the cost effectiveness of fluocinolone

    Research recommendation
    Published
    9 June 2015

  5. Further research on angioplasty and stenting to treat peripheral arterial disease causing refractory erectile dysfunction should provide clear details of patient selection. Efficacy outcomes should include procedural success (as measured by arterial imaging and blood-flow measurement), validated scoring systems of erectile dysfunction, and the duration of treatment effect. All complications should be reported. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG546/1 Question Further research on angioplasty and stenting to treat peripheral arterial disease causing refractory

    Research recommendation
    Published
    21 March 2016

  6. Further research on aortic valve reconstruction with processed bovine pericardium should address patient selection and report long-term outcomes, particularly the durability of the valve.

    Recommendation ID IPG604/1 Question Further research on aortic valve reconstruction with processed bovine pericardium should address patient

    Research recommendation
    Published
    13 November 2018

  7. Further research on electrically stimulated intravesical chemotherapy for nonmuscle-invasive bladder cancer should include randomised controlled trials compared withstandard care, which should report details of patient selection.

    Recommendation ID IPG638/1 Question Further research on electrically stimulated intravesical chemotherapy for nonmuscle-invasive bladder

    Research recommendation
    Published
    18 February 2019

  8. Further research on ex-situ machine perfusion for extracorporeal preservation of livers for transplantation should report the exact method of perfusion used (such ashypothermic or normothermic), graft survival and the use of marginal grafts.

    Recommendation ID IPG636/1 Question Further research on ex-situ machine perfusion for extracorporeal preservation of livers for transplantation

    Research recommendation
    Published
    18 February 2019

  9. Further research on endoscopic bipolar radiofrequency ablation for treating biliary obstruction caused by cancer should address: patient selection, relief of biliary obstruction, quality of life and survival.

    Recommendation ID IPG614/1 Question Further research on endoscopic bipolar radiofrequency ablation for treating biliary obstruction caused

    Research recommendation
    Published
    10 December 2018

  10. Further research, ideally in the form of randomised controlled trials, on the safety and efficacy of prostatic urethral temporary implant insertion for lower urinary tract symptoms caused by benign prostatic hyperplasia should report details of patient selection (including prostate size and the amount of median lobe enlargement), improvement in lower urinary tract symptoms in the short term and long term, re-intervention rates, and outcome measures of sexual function using established methods.

    Recommendation ID IPG641/1 Question Further research, ideally in the form of randomised controlled trials, on the safety and efficacy of

    Research recommendation
    Published
    18 February 2019

  11. Further research including the use of observational data from registries should provide information on patient selection, safety outcomes, quality of life, long-termoutcomes and the position of the procedure in the treatment pathway. NICE may update the guidance on publication of further evidence.

    Recommendation ID IPG598/1 Question Further research including the use of observational data from registries should provide information

    Research recommendation
    Published
    18 October 2018

  12. Further research in low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing should include details of patient selection, fracture site, and risk factors and comorbidities that delay fracture healing.

    Recommendation ID IPG622/1 Question Further research in low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk

    Research recommendation
    Published
    11 December 2018

  13. Further research into arthroscopic radiofrequency chondroplasty of the knee should clearly document patient selection and the types of chondral defects being treated. More evidence on long-term outcomes would be useful.

    Recommendation ID IPG493/1 Question Further research into arthroscopic radiofrequency chondroplasty of the knee should clearly document

    Research recommendation
    Published
    9 June 2015

  14. Further research in people who could have conventional cardiac pacemaker implantation should report the patient selection criteria and compare leadless pacemakers with conventional pacemakers. Follow-up should be for at least 5 years and outcomes should include adverse events, symptom relief, quality of life and device durability in the long-term.

    Recommendation ID IPG626/1 Question Further research in people who could have conventional cardiac pacemaker implantation should report

    Research recommendation
    Published
    12 December 2018

  15. Further research in superior rectal artery embolisation for haemorrhoids should report details of patient selection, and follow-up efficacy (including symptom relief), need for subsequent treatments, quality of life and safety outcomes for at least 1 year.

    Recommendation ID IPG627/1 Question Further research in superior rectal artery embolisation for haemorrhoids should report details of patient

    Research recommendation
    Published
    12 December 2018