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The appraisal has been withdrawn because Janssen withdrew their marketing authorisation on 1 May 2018. The availability of direct-acting antiviral combination treatments for hepatitis C has reduced the use of simeprevir, so the company has decided to discontinue it.
This guidance has been withdrawn because Bristol-Myers Squibb has discontinued daclatasvir (Daklinza).
This guidance has been updated and replaced by NICE technology appraisal guidance 433.
This guidance has been updated and replaced by NICE technology appraisal guidance 898.
This guidance has been updated and replaced by NICE technology appraisal guidance 933. People already having tisagenlecleucel for relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies through the Cancer Drugs Fund can continue. For those people, it will be funded by the company until they and their NHS clinician consider it appropriate to stop.
The clinical effectiveness and cost effectiveness of insulin pump therapy (TA57)
This appraisal has been updated and replaced by NICE technology appraisal guidance 151.
Brentuximab vedotin for treating CD30-positive Hodgkin lymphoma (TA446)
This guidance has been updated and replaced by NICE technology appraisal guidance 524.
Pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer (TA447)
This guidance has been updated and replaced by NICE technology appraisal guidance 531.
This guidance has been updated and replaced by NICE technology appraisal guidance 91.
Cabozantinib for previously treated advanced hepatocellular carcinoma (terminated appraisal) (TA582)
This guidance has been updated and replaced by NICE technology appraisal guidance 849.
Pembrolizumab for adjuvant treatment of resected melanoma with high risk of recurrence (TA553)
This guidance has been updated and replaced by NICE technology appraisal guidance 766.
This guidance has been updated and replaced by NICE technology appraisal guidance 683.
This guidance has been updated and replaced by NICE guideline CG40. [Replaced by NICE guideline CG171 (September 2013)]