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Guidance programme

Advice programme

Showing 4561 to 4575 of 7691 results

  1. Further data collection and research are recommended to assess the effectiveness of treatment options for bile acid diarrhoea. Consideration should be given to how well the treatments are tolerated and how they affect the severity of symptoms in the longer term.

    Recommendation ID DG44/03 Question Further data collection and research are recommended to assess the effectiveness of treatment options

    Research recommendation
    Published
    16 December 2021

  2. Further data collection and research are recommended to better understand the health-related quality of life in people with bile acid diarrhoea. Consideration should be given to how quality of life differs before and after a positive or negative test and diagnosis, and how it is affected by treatment and symptom severity.

    Recommendation ID DG44/04 Question Further data collection and research are recommended to better understand the health-related quality

    Research recommendation
    Published
    16 December 2021

  3. Further data collection and research are recommended to understand how SeHCAT (tauroselcholic [75 selenium] acid) test results affect clinical decision making.

    Recommendation ID DG44/01 Question Further data collection and research are recommended to understand how SeHCAT (tauroselcholic [75 selenium]

    Research recommendation
    Published
    16 December 2021

  4. Further data collection or research is recommended on the impact of implementing MRI fusion biopsy systems on the rate at which biopsies can be done, capacity resources and waiting times for this procedure.

    Recommendation ID DG53/2 Question Further data collection or research is recommended on the impact of implementing MRI fusion biopsy systems

    Research recommendation
    Published
    11 July 2023

  5. Further diagnostic accuracy studies, or analyses of existing data sets, are recommended to assess the accuracy of the tests included in this assessment in the following subgroups:- people who are premenopausal- people who are postmenopausal- people with suspected early stage ovarian cancer, that is, disease apparently confined to the pelvis.Future studies should be done in populations that are representative of people with suspected ovarian cancer who are assessed in NHS secondary care.

    Recommendation ID DG31/1 Question Further diagnostic accuracy studies, or analyses of existing data sets, are recommended to assess the

    Research recommendation
    Published
    18 October 2018

  6. Further good quality evidence is needed to address uncertainties about myCOPD's clinical benefits and its effect on healthcare resource use. myCOPD has potential for clinical benefits, but more evidence is needed to reduce uncertainties. The committee considered that comparative evidence is needed to show the clinical benefits of using myCOPD in 2 populations: people using it to self-manage COPD people referred to pulmonary rehabilitation For self-management, a randomised controlled trial is preferred to show the clinical benefits of myCOPD. This could be powered based on the encouraging results in the RESCUE study. However, a high-quality comparative observational study designed to minimise bias in the results may provide acceptable evidence. Outcomes such as rates of exacerbations, hospital readmissions and unscheduled care appointments should be considered alongside patient-reported outcomes such as health-related quality of life. For pulmonary rehabilitation, further evidence is needed to show the clinical benefits of myCOPD. This could be a randomised controlled trial which is powered based on the encouraging results in the TROOPER study or a well-designed comparative observational study. Key outcomes will be the CAT score and 6-minute walk test, ideally supported by additional longer-term outcomes such as rates of exacerbations and hospital admissions. Real-world data could be used to inform the uptake rates in the economic modelling. It should also include qualitative data on patient experience using myCOPD such as patient preferences and adherence.

    Recommendation ID MTG68/01 Question Further good quality evidence is needed to address uncertainties about myCOPD's clinical benefits and

    Research recommendation
    Published
    8 April 2022

  7. A randomised controlled trial is recommended to compare DyeVert Systems  with standard care. The aim of this research would be to address uncertainties  about whether using DyeVert Systems reduces AKI incidence and rate of renal  replacement therapy after using contrast media. This must include people with  stage 4 chronic kidney disease (with an estimated glomerular filtration rate  [eGFR] under 30 ml/min/1.73 m 2 ), who are at risk of AKI and need elective  coronary or peripheral angiography.

    Recommendation ID MTG60/01 Question A randomised controlled trial is recommended to compare DyeVert Systems with standard care. The aim

    Research recommendation
    Published
    5 November 2021

  8. Further primary research is recommended on the clinical effectiveness of using ELISA tests for therapeutic monitoring of TNF‑alpha inhibitors in people with rheumatoid arthritis.

    Recommendation ID DG36/1 Question Further primary research is recommended on the clinical effectiveness of using ELISA tests for therapeutic

    Research recommendation
    Published
    25 October 2019

  9. Further research and publication of observational data would be useful. Publications should describe details of patient selection, particularly in relation to previous treatments. They should also describe clinical outcomes (including all complications) and patient experience in the longer term. NICE may review the procedure on publication of further evidence.

    Recommendation ID IPG439/1 Question Further research and publication of observational data would be useful. Publications should describe

    Research recommendation
    Published
    9 June 2015

  10. Further research designed to investigate differences in health-related quality of life and the clinical effectiveness of bevacizumab in subgroups, such as those with prior taxane exposure, would be particularly useful.

    Recommendation ID TA214/1 Question Further research designed to investigate differences in health-related quality of life and the clinical

    Research recommendation
    Published
    9 June 2015

  11. Further research, ideally in the form of randomised controlled trials, on the safety and efficacy of prostatic urethral temporary implant insertion for lower urinary tract symptoms caused by benign prostatic hyperplasia should report details of patient selection (including prostate size and the amount of median lobe enlargement), improvement in lower urinary tract symptoms in the short term and long term, re-intervention rates, and outcome measures of sexual function using established methods.

    Recommendation ID IPG641/1 Question Further research, ideally in the form of randomised controlled trials, on the safety and efficacy of

    Research recommendation
    Published
    18 February 2019

  12. For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter tricuspid valve annuloplasty is limited in quantity and quality. Evidence on its safety shows there are serious but well-recognised complications. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    Recommendation ID IPG730/01 Question For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter

    Research recommendation
    Published
    4 August 2022

  13. For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter tricuspid valve leaflet repair is limited in quantity and quality. Evidence on its safety shows there are serious but well-recognised complications. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    Recommendation ID IPG731/01 Question For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter

    Research recommendation
    Published
    5 August 2022

  14. Active surveillance compared with surgery: For people with stage 1 differentiated thyroid cancer, what is the clinical and cost effectiveness of active surveillance compared with surgery?

    Recommendation ID NG230/03 Question Active surveillance compared with surgery: For people with stage 1 differentiated thyroid cancer, what

    Research recommendation
    Published
    6 January 2023

  15. FRAX and QFracture in adults receiving bone protective therapy:- What is the utility of FRAX and QFracture in adults receiving bone protective therapy?

    Recommendation ID CG146/2 Question FRAX and QFracture in adults receiving bone protective therapy:- What is the utility of FRAX and QFracture

    Research recommendation
    Published
    9 June 2015