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Guidance programme

Advice programme

Showing 4831 to 4845 of 7689 results

  1. Evidence on the efficacy of open prenatal repair of open neural tube defects in the fetus is adequate in quantity and quality. However, evidence on its safety shows serious but well recognised safety concerns for the mother and fetus. Therefore, this procedure should only be used with  special arrangements   for clinical governance, consent, and audit or research.

    Recommendation ID IPG668 Question Evidence on the efficacy of open prenatal repair of open neural tube defects in the fetus is adequate

    Research recommendation
    Published
    10 February 2020

  2. Optical coherence tomography for glaucoma:- What is the effectiveness and cost effectiveness of optical coherence tomography (OCT) for diagnosing and monitoring glaucoma?

    Recommendation ID NG81/4 Question Optical coherence tomography for glaucoma:- What is the effectiveness and cost effectiveness of optical

    Research recommendation
    Published
    18 October 2018

  3. Optimal interventional and conservative treatments at different stages of disease:- What is the optimal treatment (compression, surgery, endothermal ablation or foam sclerotherapy) for varicose veins at each of the CEAP stages, that is CEAP stages 2–3, CEAP stage 4 and CEAP stages 5–6?

    Recommendation ID CG168/5 Question Optimal interventional and conservative treatments at different stages of disease:- What is the optimal

    Research recommendation
    Published
    9 June 2015

  4. Optimal time between referral and starting intermediate care:- What is the optimal time between referral to and starting intermediate care in terms of effectiveness and cost effectiveness and in terms of people's experiences?

    Recommendation ID NG74/1 Question Optimal time between referral and starting intermediate care:- What is the optimal time between referral

    Research recommendation
    Published
    15 October 2018

  5. Organisational-level approaches for all organisations: What is the long-term impact and cost effectiveness of employee assistance programme provision on mental wellbeing?

    Recommendation ID NG212/02 Question Organisational-level approaches for all organisations: What is the long-term impact and cost effectiveness

    Research recommendation
    Published
    8 April 2022

  6. Oral antibiotic challenge for diagnosing antibiotic allergy in children:- In children who have a suspected allergy to an antibiotic, is it clinically and cost effective to proceed directly (without prior skin or intradermal tests) to a diagnostic oral antibiotic challenge rather than referring them to specialist drug allergy services?

    Recommendation ID CG183/4 Question Oral antibiotic challenge for diagnosing antibiotic allergy in children:- In children who have a suspected

    Research recommendation
    Published
    9 June 2015

  7. Organisational models for AMD diagnosis and management:- What is the long-term effectiveness, in terms of patient-relevant outcomes including visual acuityand quality of life, of different models of care that aim to reduce time from initial presentation to referral, diagnosis and treatment?

    Recommendation ID NG82/2 Question Organisational models for AMD diagnosis and management:- What is the long-term effectiveness, in terms

    Research recommendation
    Published
    13 November 2018

  8. Oral health promotion advice:- For groups at high risk of poor oral health, how effective and cost effective is it to extend an existing appointment by a few minutes, or to offer separate sessions on oral health advice?

    Recommendation ID NG30/1 Question Oral health promotion advice:- For groups at high risk of poor oral health, how effective and cost effective

    Research recommendation
    Published
    28 January 2016

  9. Organisation of care:- Is a network-based model as effective as a clinic-based model to deliver multidisciplinary care to people with motor neurone disease (MND)?

    Recommendation ID NG42/1 Question Organisation of care:- Is a network-based model as effective as a clinic-based model to deliver multidisciplinary

    Research recommendation
    Published
    21 March 2016

  10. For people with iron-deficiency anaemia, how long before surgery should oral iron supplementation be started, and what is the clinical and cost effectiveness of daily oral iron compared with oral iron given on alternate days?

    Recommendation ID NG180/2 Question For people with iron-deficiency anaemia, how long before surgery should oral iron supplementation be

    Research recommendation
    Published
    26 October 2020

  11. Organisation of care:- What is the clinical and cost effectiveness of alternative approaches to organising primary care compared with usual care for people with multimorbidity?

    Recommendation ID NG56/1 Question Organisation of care:- What is the clinical and cost effectiveness of alternative approaches to organising

    Research recommendation
    Published
    18 October 2016

  12. What is the efficacy of reduced dose oral isotretinoin in the management of acne vulgaris?

    Recommendation ID NG198/1 Question What is the efficacy of reduced dose oral isotretinoin in the management of acne vulgaris? Any

    Research recommendation
    Published
    3 May 2024

  13. Orthostatic hypotension treatment:- For people with Parkinson's disease, what is the most effective pharmacological treatment for orthostatic hypotension?Particular interventions and comparisons of interest are:- midodrine compared with fludrocortisone (primary comparison)- pyridostigmine- ephedrine - pseudoephedrine.

    Recommendation ID NG71/2 Question Orthostatic hypotension treatment:- For people with Parkinson's disease, what is the most effective pharmacological

    Research recommendation
    Published
    15 October 2018

  14. Other specialist management:- What specialist management is effective for people whose symptoms do not respond to PPIs despite optimum primary care, or for people whose symptoms return after surgery?

    Recommendation ID CG184/4 Question Other specialist management:- What specialist management is effective for people whose symptoms do not

    Research recommendation
    Published
    9 June 2015

  15. Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without significant complications?

    Recommendation ID NG124/4 Question Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without...

    Research recommendation
    Published
    16 August 2019