Search results

Skip to results

Area of interest

Area of interest

Type

Type

Status

Status

Last updated

Last updated

Guidance programme

Advice programme

Showing 4441 to 4455 of 7691 results

  1. The committee also noted that the additional evidence exploring the relationship between radiological measures of bone defects (that is, the Rickets Severity Score and the Radiographic Global Impression of Change) and health-related quality of life would help to address several key uncertainties in the economic analysis.

    Recommendation ID HST8/2 Question The committee also noted that the additional evidence exploring the relationship between radiological

    Research recommendation
    Published
    22 March 2019

  2. Additional methodological research is needed to determine the most appropriate model structures to assess the benefit arising from radiation dose reduction. Additional work is needed to assess when the radiation-induced cancers actually occur and the impact of the timing of the emergence of cancer on health status.

    Recommendation ID DG1/2 Question Additional methodological research is needed to determine the most appropriate model structures to assess

    Research recommendation
    Published
    9 June 2015

  3. Additional maintenance therapy for asthma uncontrolled on a moderate dose of ICS plus LABA with or without LTRA:- What is the clinical and cost effectiveness of offering additional maintenance therapy to adults, young people and children with asthma that is uncontrolled on a moderate dose of ICS plus LABA with or without LTRA?

    Recommendation ID NG80/8 Question Additional maintenance therapy for asthma uncontrolled on a moderate dose of ICS plus LABA with or without

    Research recommendation
    Published
    18 October 2018

  4. Adenoma types and risk of colorectal cancer:- Does the risk of colorectal cancer depend on the type of adenoma?

    Recommendation ID CG118/4 Question Adenoma types and risk of colorectal cancer:- Does the risk of colorectal cancer depend on the type

    Research recommendation
    Published
    9 June 2015

  5. Adjuvant luteal phase support treatments in IVF:- Further research is needed to assess the efficacy of adjuvant luteal phase support treatments such as low-dose aspirin, heparin, prednisolone, immunoglobulins and/or fat emulsions.

    Recommendation ID CG156/3 Question Adjuvant luteal phase support treatments in IVF:- Further research is needed to assess the efficacy

    Research recommendation
    Published
    9 June 2015

  6. Adults' uptake of and engagement with interventions for social anxiety disorder:- What methods are effective in improving uptake of and engagement with interventions for adults with social anxiety disorder?

    Recommendation ID CG159/1 Question Adults' uptake of and engagement with interventions for social anxiety disorder:- What methods are effective

    Research recommendation
    Published
    9 June 2015

  7. Advance statements and decisions:- What forms of management of violence and aggression do service users prefer and do advance statements and decisions have an important role in management and prevention?

    Recommendation ID NG10/3 Question Advance statements and decisions:- What forms of management of violence and aggression do service users

    Research recommendation
    Published
    1 October 2015

  8. AEDs and pregnancy: What is the malformation rate and longer term neurodevelopmental outcome of children born to mothers who have taken AEDs during pregnancy?

    Recommendation ID CG137/5 Question AEDs and pregnancy: What is the malformation rate and longer term neurodevelopmental outcome of children

    Research recommendation
    Published
    13 August 2021

  9. Agitation and delirium:- What is the best way to control delirium, with or without agitation, in the dying person, without causing undue sedation and without shortening life?

    Recommendation ID NG31/2 Question Agitation and delirium:- What is the best way to control delirium, with or without agitation, in the

    Research recommendation
    Published
    27 January 2016

  10. A high-quality test accuracy study is needed for the BRAHMS sFlt‑1 Kryptor/BRAHMS PLGF plus Kryptor PE ratio test, using thresholds defined by the company, done in a population independent from that used to establish the test's thresholds, and with the test used as intended in the NHS. Further research is recommended on repeat PLGF (placental growth factor)‑based testing, with standard clinical assessment, in women presenting with suspected preterm pre-eclampsia, who have had a previous PLGF‑based test result (see section 3.7 ). This should include: - exploring the different scenarios in which repeat testing may be indicated - the appropriate intervals between PLGF‑based tests - the diagnostic accuracy of repeat PLGF‑based testing in women with suspected preterm pre-eclampsia. Further research is recommended into how well the tests work when women are pregnant with more than 1 baby to find out if different cut-offs are needed (see section 3.15 ).

    Recommendation ID DG49/01 Question A high-quality test accuracy study is needed for the BRAHMS sFlt‑1 Kryptor/BRAHMS PLGF plus Kryptor

    Research recommendation
    Published
    4 August 2022

  11. What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the home?

    Recommendation ID NG149/3 Question What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the

    Research recommendation
    Published
    10 February 2020

  12. Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung function in infants and children with cystic fibrosis?

    Recommendation ID NG78/2 Question Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung

    Research recommendation
    Published
    6 November 2018

  13. Allogeneic stem cell transplantation:- What is the effectiveness of combined autologous–allogeneic stem cell transplantation compared with autologous stem cell transplantation, plus consolidation and maintenance treatment in chemosensitive patients at first response or first relapse?

    Recommendation ID NG35/4 Question Allogeneic stem cell transplantation:- What is the effectiveness of combined autologous–allogeneic stem

    Research recommendation
    Published
    5 April 2016

  14. Additional research could help address uncertainties in the evidence, although the case for cost savings remains unlikely. Although the committee acknowledged that the Game et al. (2018) RCT was well conducted, it felt that additional research could help resolve some uncertainties around the cost and clinical case for 3C Patch. Specifically, research identifying the most appropriate stopping rule, and the associated clinical outcomes of implementing the rule, would help address key uncertainties within the cost case. Additional collection of resource use data on unhealed hard-to-heal ulcers could also reduce uncertainty in the cost case. Further to this, evidence could be collected on an UrgoStart-experienced population, as this would be reflective of current NHS care. Clinical experts thought a trial on this population would be feasible. The committee concluded that although further research could be done, on balance it was unlikely to result in a cost-saving case for 3C Patch based on the decision problem evaluated in this guidance

    Recommendation ID MTG66/01 Question Additional research could help address uncertainties in the evidence, although the case for cost savings

    Research recommendation
    Published
    8 April 2022

  15. ALT values for children and young people:- Further research should be undertaken to examine whether the upper limit of normal ALT values for adults (below 30 IU/ml for males and below 19 IU/ml for females) are appropriate for use in children and young people with chronic hepatitis B when making decisions on when to initiate treatment.

    Recommendation ID CG165/2 Question ALT values for children and young people:- Further research should be undertaken to examine whether

    Research recommendation
    Published
    9 June 2015