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This advice has been updated and replaced by NICE guideline NG220.
Lubiprostone for treating chronic idiopathic constipation (TA318)
This guidance has been withdrawn because Takeda has discontinued lubiprostone (Amitiza).
Beta interferon and glatiramer acetate for the treatment of multiple sclerosis (TA32)
This guidance has been updated and replaced by NICE technology appraisal guidance 527.
This guidance has been updated and replaced by NICE technology appraisal guidance 604.
This guidance has been updated and replaced by NICE technology appraisal guidance 402.
The clinical effectiveness and cost effectiveness of sibutramine for obesity (TA31)
This guidance has been replaced by NICE guideline CG43.
This guidance has been updated and replaced by NICE technology appraisal guidance 340.
This guidance has been updated and replaced by NICE technology appraisal guidance 953.
This guidance has been replaced by NICE guideline CG81.
Ruxolitinib for disease-related splenomegaly or symptoms in adults with myelofibrosis (TA289)
This guidance has been updated and replaced by NICE technology appraisal guidance 386.
Pegloticase for treating severe debilitating chronic tophaceous gout (TA291)
The guidance has been withdrawn because pegloticase (Krystexxa) no longer has a marketing authorisation. See the European Medicines Agency product information.
This guidance has been updated and replaced by NICE technology appraisal guidance TA421.
This guideance has been updated and replaced by NICE technology appraisal guidance 422.
We have withdrawn this guidance. Inceptua has stopped marketing Ocriplasmin (Jetrea) and its marketing authorisation has been withdrawn.
Bosutinib for previously treated chronic myeloid leukaemia (TA299)
This guidance has been updated and replaced by NICE technology appraisal guidance 401.